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Anti-Cip4 Antibody (7W163)
😃Good
Catalog No. TMAB-04360
Anti-Cip4 Antibody (7W163) is a Rabbit antibody targeting Cip4. Anti-Cip4 Antibody (7W163) can be used in WB.
Anti-Cip4 Antibody (7W163)
Anti-Cip4 Antibody (7W163)
😃Good
Catalog No. TMAB-04360
Anti-Cip4 Antibody (7W163) is a Rabbit antibody targeting Cip4. Anti-Cip4 Antibody (7W163) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Cip4 Antibody (7W163) is a Rabbit antibody targeting Cip4. Anti-Cip4 Antibody (7W163) can be used in WB. |
| Ig Type | IgG |
| Clone | 7W163 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB=1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Lysosome. Golgi apparatus. Cell membrane. Cell projection, phagocytic cup. Note=Translocates to the plasma membrane in response to insulin stimulation, and this may require active RHOQ (By similarity). Localizes to cortical regions coincident with F-actin, to lysosomes and to sites of phagocytosis in macrophages. Also localizes to the Golgi, and this requires AKAP9. Isoform 5: Cytoplasm, perinuclear region. |
| Tissue Specificity | Expressed in brain, colon, heart, kidney, liver, lung, megakaryocyte, ovary, pancreas, peripheral blood lymphocytes, placenta, prostate, skeletal muscle, small intestine, spleen, testis, thymus and trachea. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity).Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. |
| Immunogen | A synthesized peptide: human TRIP10 |
| Antigen Species | Human |
| Gene Name | TRIP10 |
| Gene ID | |
| Protein Name | Cdc42-interacting protein 4 |
| Uniprot ID | |
| Function | Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL. |
| Molecular Weight | Theoretical: 68 kDa. Actual: 75 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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