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Anti-SR-BI/SCARB1 Antibody (1A957)
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Catalog No. TMAC-03690
Alias SR-BI, SRBI, SR-B1, Srb1, scavenger receptor class B, member 1, mSR-BI, Hlb398, Hdlq1, D5Ertd460e, Cla-1, Cla1, Cd36l1, CD36, AI120173
Anti-SR-BI/SCARB1 Antibody (1A957) is a Rabbit antibody targeting SR-BI/SCARB1. Anti-SR-BI/SCARB1 Antibody (1A957) can be used in WB,ICC,IHC,FCM.
Anti-SR-BI/SCARB1 Antibody (1A957)
Anti-SR-BI/SCARB1 Antibody (1A957)
😃Good
Catalog No. TMAC-03690Alias SR-BI, SRBI, SR-B1, Srb1, scavenger receptor class B, member 1, mSR-BI, Hlb398, Hdlq1, D5Ertd460e, Cla-1, Cla1, Cd36l1, CD36, AI120173
Anti-SR-BI/SCARB1 Antibody (1A957) is a Rabbit antibody targeting SR-BI/SCARB1. Anti-SR-BI/SCARB1 Antibody (1A957) can be used in WB,ICC,IHC,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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| Description | Anti-SR-BI/SCARB1 Antibody (1A957) is a Rabbit antibody targeting SR-BI/SCARB1. Anti-SR-BI/SCARB1 Antibody (1A957) can be used in WB,ICC,IHC,FCM. |
| Synonyms | SR-BI, SRBI, SR-B1, Srb1, scavenger receptor class B, member 1, mSR-BI, Hlb398, Hdlq1, D5Ertd460e, Cla-1, Cla1, Cd36l1, CD36, AI120173 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of Scavenging Receptor SR-BI on different lysates using anti-Scavenging Receptor SR-BI antibody at 1/1,000 dilution. Positive control: Lane 1: Human liver, Lane 2: Mouse liver. 2. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Scavenging Receptor SR-BI antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-Scavenging Receptor SR-BI antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-Scavenging Receptor SR-BI antibody. Counter stained with hematoxylin. 5. ICC staining Scavenging Receptor SR-BI in CRC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. ICC staining Scavenging Receptor SR-BI in PC-12 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| Application | |
| Recommended Dose | WB: 1:1000-5000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The macrophage class A scavenger receptors (SR-A) type I and II mediate the uptake of modified low density lipoprotein (LDL), while the scavenger receptor class B type 1 (SR-B1) mediates the selective uptake of cholesterol and cholesterol esters (CE) from HDLs into cells. SREC, Ox-LDL-R1, SR-A and SR-B1 may all be involved in the early development of atherosclerosis. SR-B1, an integral membrane protein, acts as a receptor for various ligands, including apoptotic cells, cholesterol ester, phospholipids, lipoproteins and phosphatidyl-serine. SR-B1, which may be involved in phagocytosis of apoptotic cells, enables the movement of cholesterol between the cell surface and extracellular donors and acceptors. Although it is widely expressed, SR-B1 localizes primarily to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 80 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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