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Anti-RANBP9 Antibody (9K369)

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Catalog No. TMAB-12078

Anti-RANBP9 Antibody (9K369) is a Rabbit antibody targeting RANBP9. Anti-RANBP9 Antibody (9K369) can be used in FCM, ICC/IF, WB.

Anti-RANBP9 Antibody (9K369)

Anti-RANBP9 Antibody (9K369)

😃Good
Catalog No. TMAB-12078
Anti-RANBP9 Antibody (9K369) is a Rabbit antibody targeting RANBP9. Anti-RANBP9 Antibody (9K369) can be used in FCM, ICC/IF, WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1487-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-RANBP9 Antibody (9K369) is a Rabbit antibody targeting RANBP9. Anti-RANBP9 Antibody (9K369) can be used in FCM, ICC/IF, WB.
Ig Type
IgG
Clone
9K369
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
FCM=1:50-100; ICC/IF=1:50-200; WB=1:1000-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm, cytosol. Nucleus. Note==Predominantly cytoplasmic. A phosphorylated form is associated with the plasma membrane.
Tissue SpecificityUbiquitously expressed, with highest levels in testes, placenta, heart, and muscle, and lowest levels in lung. Within the brain, expressed predominantly by neurons in the gray matter of cortex, the granular layer of cerebellum and the Purkinje cells.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundMay act as scaffolding protein, and as adapter protein to couple membrane receptors to intracellular signaling pathways (Probable). Acts as a mediator of cell spreading and actin cytoskeleton rearrangement.Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.
Antigen Details
Immunogen
A synthesized peptide: human RanBP9
Antigen Species
Human
Gene Name
RANBP9
Gene ID
Protein Name
RAN binding protein 9
Uniprot ID
Function
May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA.
Chemical Properties
Molecular WeightTheoretical: 78 kDa. Actual: 91 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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