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Anti-SNCA Antibody (9C948) (Synonyms: PD1, PARK4, PARK1, NACP)
Catalog No. TMAH-01115 Copy Product Info
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Anti-SNCA Antibody (9C948) is an antibody targeting SNCA. Anti-SNCA Antibody (9C948) can be used in ELISA,IHC.
Anti-SNCA Antibody (9C948)
Copy Product Info🥰Excellent
Catalog No. TMAH-01115
Synonyms PD1, PARK4, PARK1, NACP
Anti-SNCA Antibody (9C948) is an antibody targeting SNCA. Anti-SNCA Antibody (9C948) can be used in ELISA,IHC.
Anti-SNCA Antibody
(9C948)
(9C948)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $207 | 7-10 days | 7-10 days | |
| 100 μL | $347 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-SNCA Antibody (9C948) is an antibody targeting SNCA. Anti-SNCA Antibody (9C948) can be used in ELISA,IHC. |
| Synonyms | PD1, PARK4, PARK1, NACP |
| Ig Type | Rabbit IgG |
| Clone | 9C948 |
| Reactivity | Human |
| Verified Activity | IHC image of TMAH-01115 diluted at 1:100 and staining in paraffin-embedded human skin tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| Application | |
| Recommended Dose | IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cytoplasm. Membrane. Nucleus. Cell junction, synapse. Secreted. |
| Tissue Specificity | Highly expressed in presynaptic terminals in the central nervous system. Expressed principally in brain. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5. This chaperone activity is important to sustain normal SNARE-complex assembly during aging. Plays also a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human Alpha Synuclein |
| Antigen Species | Human |
| Gene Name | SNCA |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Neuroscience |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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