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CD42b/GP1BA Protein, Human, Recombinant (aa 17-531, His) is expressed in HEK293 Cells. The accession number is P07359.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 μg | $47 | 7-10 days | 7-10 days | |
| 10 μg | $74 | 7-10 days | 7-10 days | |
| 20 μg | $118 | 7-10 days | 7-10 days | |
| 50 μg | $228 | 7-10 days | 7-10 days | |
| 100 μg | $405 | 7-10 days | 7-10 days | |
| 200 μg | $716 | 7-10 days | 7-10 days | |
| 500 μg | $1,520 | 7-10 days | 7-10 days |
| Biological Activity | Immobilized Human CD42b, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-CD42b Antibody, hFc Tag with the EC50 of 4.0 ng/ml determined by ELISA. |
| Description | CD42b/GP1BA Protein, Human, Recombinant (aa 17-531, His) is expressed in HEK293 Cells. The accession number is P07359. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | P07359 |
| Synonyms | VWDP,GPIbα,GPIbalpha,GPIbA,GP1B,glycoprotein Ib (platelet), α polypeptide,glycoprotein Ib (platelet), alpha polypeptide,DBPLT3,CD42b-α,CD42b-alpha,CD42B,BSS,BDPLT3,BDPLT1 |
| Construction | His17-Leu531 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Molecular Weight | 57.6 kDa (Predicted); 110-115 kDa (Due to glycosylation) |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| Research Background | Absence of the CD42 complex leads to the Bernard-Soulier syndrome (BSS), which is a bleeding disorder characterized by thrombocytopenia and giant platelets. So far, mutations have been found in the genes encoding CD42a, CD42b and CD42c in patients with BSS**. |
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