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Anti-HDAC10 Antibody (7E996)
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Catalog No. TMAC-01772
Alias Polyamine deacetylase HDAC10, Histone deacetylase 10 (HD10), HDAC10
Anti-HDAC10 Antibody (7E996) is a Rabbit antibody targeting HDAC10. Anti-HDAC10 Antibody (7E996) can be used in WB,ICC,IP.
Anti-HDAC10 Antibody (7E996)
Anti-HDAC10 Antibody (7E996)
😃Good
Catalog No. TMAC-01772Alias Polyamine deacetylase HDAC10, Histone deacetylase 10 (HD10), HDAC10
Anti-HDAC10 Antibody (7E996) is a Rabbit antibody targeting HDAC10. Anti-HDAC10 Antibody (7E996) can be used in WB,ICC,IP.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-HDAC10 Antibody (7E996) is a Rabbit antibody targeting HDAC10. Anti-HDAC10 Antibody (7E996) can be used in WB,ICC,IP. |
| Synonyms | Polyamine deacetylase HDAC10, Histone deacetylase 10 (HD10), HDAC10 |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Western blot analysis of HDAC10 on HepG2 cells lysates using anti-HDAC10 antibody at 1/1,000 dilution. 2. ICC staining HDAC10 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining HDAC10 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining HDAC10 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| Application | |
| Recommended Dose | WB: 1:1000; ICC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Histone deacetylases (HDACs) play an important role in the modification of chromatin structure and thus in the suppression and activation of transcription and cellular differentiation. There are 11 members in the HDAC family that are divided into four classes. Class I HDACs represent homologs of the yeast histone deacetylase Rpd3, class II HDACs share strong homology with the yeast histone deacetylase Hda1, class III HDACs are closely related to the yeast Sir2 protein and class IV HDACs comprise histone deacetylase 11 (HDAC11)-related enzymes. HDAC10, also known as HD10, is a member of the class II HDACs. It contains an N-terminal Hda1p-related catalytic domain and a unique C-terminal leucine-rich domain. HDAC10 is ubiquitously expressed and can shuttle between the cytoplasm and nucleus in response to celllular signals. It is able to repress transcription and, like other class II HDAC members, its enzymatic activity is inhibited by Trichostatin A (TSA). |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 43 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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