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DCLK1 Protein, Human, Recombinant (aa 1-740, GST)

(Synonyms: Serine/threonine-protein kinase DCLK1, KIAA0369, DCLK1, DCDC3A, DCAMKL1) Copy Product Info

Synonyms: Serine/threonine-protein kinase DCLK1, KIAA0369, DCLK1, DCDC3A, DCAMKL1

Catalog No. TMPC-00211 Copy Product Info
DCLK1 Protein, Human, Recombinant (aa 1-740, GST) is expressed in Baculovirus-Insect Cells. The accession number is O15075.
DCLK1 Protein, Human, Recombinant (aa 1-740, GST)
Pack SizePriceUSA StockGlobal StockQuantity
10 µg$1,39035 days35 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
The specific activity of DCAMKL1 was determined to be 3.0-3.9 nmol /min/mg by ADP-Glo kinase assay.
Description
DCLK1 Protein, Human, Recombinant (aa 1-740, GST) is expressed in Baculovirus-Insect Cells. The accession number is O15075.
Species
Human
Expression System
Baculovirus-Insect Cells
TagN-GST
Accession NumberO15075
ConstructionRecombinant full length human DCAMKL1 was expressed by baculovirus in Sf9 cells using an N-terminal GST tag.
Protein Purity
>70% as determined by SDS-PAGE.
DCLK1 Protein, Human, Recombinant (aa 1-740, GST)
FormulationSupplied as sterile 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, and 25% glycerol.
SynonymsSerine/threonine-protein kinase DCLK1, KIAA0369, DCLK1, DCDC3A, DCAMKL1
Research Background
DCAMKL1, also known as DCLK1, is a member of the protein kinase superfamily and the doublecortin family. It contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. DCAMKL1 is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. Its microtubule-polymerizing activity is independent of its protein kinase activity. DCAMKL1 may be involved in a calcium-signaling pathway controlling neuronal migration in the developing brain. It may also participate in functions of the mature nervous system.
Chemical Properties
Molecular Weight~110 kDa
Storage & Solubility Information
ShippingEnzymes are highly recommended to be shipped at frozen temperature with dry ice. Shipment made at ambient temperature may seriously affect the activity of the ordered products.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: DCLK1 Protein, Human, Recombinant (aa 1-740, GST) chemical structure | DCLK1 Protein, Human, Recombinant (aa 1-740, GST) molecular weight