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Anti-Mad2L1 Antibody (1G292)
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Catalog No. TMAB-08497
Anti-Mad2L1 Antibody (1G292) is a Rabbit antibody targeting Mad2L1. Anti-Mad2L1 Antibody (1G292) can be used in ICC/IF.
Anti-Mad2L1 Antibody (1G292)
Anti-Mad2L1 Antibody (1G292)
Copy Product Info😃Good
Catalog No. TMAB-08497
Anti-Mad2L1 Antibody (1G292) is a Rabbit antibody targeting Mad2L1. Anti-Mad2L1 Antibody (1G292) can be used in ICC/IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Mad2L1 Antibody (1G292) is a Rabbit antibody targeting Mad2L1. Anti-Mad2L1 Antibody (1G292) can be used in ICC/IF. |
| Ig Type | IgG |
| Clone | 1G292 |
| Reactivity | Human |
| Verified Activity | A549 cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Antibody incubation with (Mad2L1) monoclonal Antibody, Unconjugated (TMAB-08497) 1:100, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (blue) was used to stain the cell nuclei. |
| Application | |
| Recommended Dose | ICC/IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Chromosome, centromere, kinetochore. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. [provided by RefSeq, Jul 2008] |
| Immunogen | Recombinant Protein: human Mad2L1 protein |
| Antigen Species | Human |
| Gene Name | MAD2L1 |
| Gene ID | |
| Protein Name | Mitotic spindle assembly checkpoint protein MAD2A |
| Uniprot ID | |
| Function | Component of the spindle-assembly checkpoint thatprevents the onset of anaphase until all chromosomes are properlyaligned at the metaphase plate. Required for the execution of themitotic checkpoint which monitors the process ofkinetochore-spindle attachment and inhibits the activity of theanaphase promoting complex by sequestering CDC20 until allchromosomes are aligned at the metaphase plate. |
| Molecular Weight | Theoretical: 23 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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