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Anti-Mad2L1 Antibody (1G292)

Catalog No. TMAB-08497 Copy Product Info
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Anti-Mad2L1 Antibody (1G292) is a Rabbit antibody targeting Mad2L1. Anti-Mad2L1 Antibody (1G292) can be used in ICC/IF.

Anti-Mad2L1 Antibody (1G292)

Copy Product Info
🥰Excellent
Catalog No. TMAB-08497

Anti-Mad2L1 Antibody (1G292) is a Rabbit antibody targeting Mad2L1. Anti-Mad2L1 Antibody (1G292) can be used in ICC/IF.

Anti-Mad2L1 Antibody
(1G292)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2617-10 days7-10 days
100 μL$4717-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Mad2L1 Antibody (1G292) is a Rabbit antibody targeting Mad2L1. Anti-Mad2L1 Antibody (1G292) can be used in ICC/IF.
Ig Type
IgG
Clone
1G292
Reactivity
Human
Verified Activity
A549 cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Antibody incubation with (Mad2L1) monoclonal Antibody, Unconjugated (TMAB-08497) 1:100, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (blue) was used to stain the cell nuclei.
Application
Recommended Dose
ICC/IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Chromosome, centromere, kinetochore. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundMAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
Recombinant Protein: human Mad2L1 protein
Antigen Species
Human
Gene Name
MAD2L1
Gene ID
Protein Name
Mitotic spindle assembly checkpoint protein MAD2A
Uniprot ID
Function
Component of the spindle-assembly checkpoint thatprevents the onset of anaphase until all chromosomes are properlyaligned at the metaphase plate. Required for the execution of themitotic checkpoint which monitors the process ofkinetochore-spindle attachment and inhibits the activity of theanaphase promoting complex by sequestering CDC20 until allchromosomes are aligned at the metaphase plate.
Chemical Properties
Molecular WeightTheoretical: 23 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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