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Anti-PAR6 Antibody (2R536)
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Catalog No. TMAB-09984 Copy Product Info
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Anti-PAR6 Antibody (2R536) is a Rabbit antibody targeting PAR6. Anti-PAR6 Antibody (2R536) can be used in WB,IP,FCM.
Anti-PAR6 Antibody
(2R536)
(2R536)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-PAR6 Antibody (2R536) is a Rabbit antibody targeting PAR6. Anti-PAR6 Antibody (2R536) can be used in WB,IP,FCM. |
| Ig Type | IgG |
| Clone | 2R536 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IP: 1:20-50; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Cell membrane. Cell projection, ruffle. Cell junction, tight junction. Colocalizes with GTP-bound CDC42 or RAC1 at membrane ruffles and with PARD3 and PRKCI at epithelial tight junctions. |
| Tissue Specificity | Expressed in pancreas, skeletal muscle, brain and heart. Weakly expressed in kidney and placenta. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. |
| Immunogen | A synthesized peptide: human PAR6 alpha |
| Antigen Species | Human |
| Gene Name | PARD6A |
| Gene ID | |
| Protein Name | Partitioning defective 6 homolog alpha |
| Uniprot ID | |
| Function | Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. |
| Molecular Weight | Theoretical: 37 kDa. Actual: 37 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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