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Anti-PAR6 Antibody (2R536)

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Catalog No. TMAB-09984

Anti-PAR6 Antibody (2R536) is a Rabbit antibody targeting PAR6. Anti-PAR6 Antibody (2R536) can be used in WB,IP,FCM.

Anti-PAR6 Antibody (2R536)

Anti-PAR6 Antibody (2R536)

😃Good
Catalog No. TMAB-09984
Anti-PAR6 Antibody (2R536) is a Rabbit antibody targeting PAR6. Anti-PAR6 Antibody (2R536) can be used in WB,IP,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1497-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-PAR6 Antibody (2R536) is a Rabbit antibody targeting PAR6. Anti-PAR6 Antibody (2R536) can be used in WB,IP,FCM.
Ig Type
IgG
Clone
2R536
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-2000; IP: 1:20-50; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Cell membrane. Cell projection, ruffle. Cell junction, tight junction. Colocalizes with GTP-bound CDC42 or RAC1 at membrane ruffles and with PARD3 and PRKCI at epithelial tight junctions.
Tissue SpecificityExpressed in pancreas, skeletal muscle, brain and heart. Weakly expressed in kidney and placenta.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundAdapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Antigen Details
Immunogen
A synthesized peptide: human PAR6 alpha
Antigen Species
Human
Gene Name
PARD6A
Gene ID
Protein Name
Partitioning defective 6 homolog alpha
Uniprot ID
Function
Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Chemical Properties
Molecular WeightTheoretical: 37 kDa. Actual: 37 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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