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Anti-PTPRR Antibody (6N614)

😃Good
Catalog No. TMAB-11936

Anti-PTPRR Antibody (6N614) is a Rabbit antibody targeting PTPRR. Anti-PTPRR Antibody (6N614) can be used in WB.

Anti-PTPRR Antibody (6N614)

Anti-PTPRR Antibody (6N614)

😃Good
Catalog No. TMAB-11936
Anti-PTPRR Antibody (6N614) is a Rabbit antibody targeting PTPRR. Anti-PTPRR Antibody (6N614) can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-PTPRR Antibody (6N614) is a Rabbit antibody targeting PTPRR. Anti-PTPRR Antibody (6N614) can be used in WB.
Ig Type
IgG
Clone
6N614
Reactivity
Mouse,Rat (predicted:Human)
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane and Cytoplasm > perinuclear region. Locates to the perinuclear areas within the cytoplasm.
Tissue SpecificityExpressed in brain, placenta, small intestine, stomach, uterus and weakly in the prostate. Isoform alpha has been observed only in the brain. Isoform gamma is expressed in brain, placenta and uterus. Isoform delta is expressed in brain, kidney, placenta, prostate, small intestine and uterus.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundSequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity).
Antigen Details
Immunogen
A synthesized peptide: human PTPRR
Antigen Species
Human
Gene Name
PTPRR
Gene ID
Protein Name
Receptor-type tyrosine-protein phosphatase R
Uniprot ID
Function
Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus.
Chemical Properties
Molecular WeightTheoretical: 74 kDa. Actual: 74 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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