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Anti-LAMP1 Antibody (2T47)

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Catalog No. TMAB-08210

Anti-LAMP1 Antibody (2T47) is a Rabbit antibody targeting LAMP1. Anti-LAMP1 Antibody (2T47) can be used in ICC/IF, IF, IHC-Fr, IHC-P, WB.

Anti-LAMP1 Antibody (2T47)

Anti-LAMP1 Antibody (2T47)

😃Good
Catalog No. TMAB-08210
Anti-LAMP1 Antibody (2T47) is a Rabbit antibody targeting LAMP1. Anti-LAMP1 Antibody (2T47) can be used in ICC/IF, IF, IHC-Fr, IHC-P, WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4737-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-LAMP1 Antibody (2T47) is a Rabbit antibody targeting LAMP1. Anti-LAMP1 Antibody (2T47) can be used in ICC/IF, IF, IHC-Fr, IHC-P, WB.
Ig Type
IgG
Clone
2T47
Reactivity
Human
Application
ICC/IF
IF
IHC-Fr
IHC-P
WB
Recommended Dose
ICC/IF=1:50-200; IF=1:200-1000; IHC-Fr=1:200-1000; IHC-P=1:200-1000; WB=1:1000-5000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=This protein shuttles between lysosomes, endosomes, and the plasma membrane.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundLysosome associated membrane protein (LAMP1), also known as lgp120 or lgpA, is a type 1 integral membrane protein that is transported from trans Golgi networks to endosomes and then lysosomes. Upon cell activation, LAMP1 transfer to the plasma membrane is dependent on a carboxyl terminal tyrosine based motif (YXXI). Perturbation in the spacing between the tyrosine based motif relative to the membrane abolishes lysosome localization of LAMP1. This mutant protein then cycles between the plasma membrane and the endosome. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.
Antigen Details
Immunogen
Recombinant Protein: human LAMP1 protein
Antigen Species
Human
Gene Name
LAMP1
Gene ID
3916
Protein Name
Lysosome-associated membrane glycoprotein 1
Uniprot ID
P11279
Function
Presents carbohydrate ligands to selectins. Also mplicated in tumor cell metastasis.
Chemical Properties
Molecular WeightTheoretical: 45 kDa. Actual: 110-120 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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