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Anti-ADRA1A Antibody (6P896)

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Catalog No. TMAB-02355

Anti-ADRA1A Antibody (6P896) is a Rabbit antibody targeting ADRA1A. Anti-ADRA1A Antibody (6P896) can be used in WB,ICC/IF,FCM.

Anti-ADRA1A Antibody (6P896)

Anti-ADRA1A Antibody (6P896)

😃Good
Catalog No. TMAB-02355
Anti-ADRA1A Antibody (6P896) is a Rabbit antibody targeting ADRA1A. Anti-ADRA1A Antibody (6P896) can be used in WB,ICC/IF,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1487-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-ADRA1A Antibody (6P896) is a Rabbit antibody targeting ADRA1A. Anti-ADRA1A Antibody (6P896) can be used in WB,ICC/IF,FCM.
Ig Type
IgG
Clone
6P896
Reactivity
Human,Mouse,Rat
Application
WB
ICC/IF
FCM
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Location at the nuclear membrane facilitates heterooligomerization and regulates ERK-mediated signaling in cardiac myocytes. Colocalizes with GNAQ, PLCB1 as well as LAP2 at the nuclear membrane of cardiac myocytes.
Tissue SpecificityExpressed in heart, brain, liver and prostate, but not in kidney, lung, adrenal, aorta and pituitary. Within the prostate, expressed in the apex, base, periurethral and lateral lobe. Isoform 4 is the most abundant isoform expressed in the prostate with high levels also detected in liver and heart.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundThis alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins.
Antigen Details
Immunogen
A synthesized peptide: human ADRA1A
Antigen Species
Human
Gene Name
ADRA1A
Gene ID
148
Protein Name
alpha-1A adrenergic receptor
Uniprot ID
P35348
Function
This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes.
Chemical Properties
Molecular WeightTheoretical: 51 kDa. Actual: 52 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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