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Anti-Cdc23 Antibody (5O347)
🥰Excellent
Catalog No. TMAB-04115
Antibody Type: Recombinant Rabbit Monoclonal
Application: WB,ICC/IF
Reactivity: Human (predicted:Mouse,Rat)
Anti-Cdc23 Antibody (5O347)
Anti-Cdc23 Antibody (5O347)
🥰Excellent
Catalog No. TMAB-04115
Antibody Type: Recombinant Rabbit Monoclonal
Application: WB,ICC/IF
Reactivity: Human (predicted:Mouse,Rat)
Application: WB,ICC/IF
Reactivity: Human (predicted:Mouse,Rat)
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Cdc23 Antibody (5O347) is a Rabbit antibody targeting Cdc23. Anti-Cdc23 Antibody (5O347) can be used in WB,ICC/IF. |
| Ig Type | IgG |
| Clone | 5O347 |
| Reactivity | Human (predicted:Mouse,Rat) |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. [provided by RefSeq, Jul 2008] |
| Immunogen | A synthesized peptide: human CDC23 |
| Antigen Species | Human |
| Gene Name | CDC23 |
| Gene ID | |
| Protein Name | Cell division cycle protein 23 homolog |
| Uniprot ID | |
| Function | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. |
| Molecular Weight | Theoretical: 69 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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