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Anti-Glucocorticoid receptor Antibody (5H652)
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Catalog No. TMAB-06534
Anti-Glucocorticoid receptor Antibody (5H652) is a Rabbit antibody targeting Glucocorticoid receptor. Anti-Glucocorticoid receptor Antibody (5H652) can be used in WB,FCM.
Anti-Glucocorticoid receptor Antibody (5H652)
Anti-Glucocorticoid receptor Antibody (5H652)
😃Good
Catalog No. TMAB-06534
Anti-Glucocorticoid receptor Antibody (5H652) is a Rabbit antibody targeting Glucocorticoid receptor. Anti-Glucocorticoid receptor Antibody (5H652) can be used in WB,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Glucocorticoid receptor Antibody (5H652) is a Rabbit antibody targeting Glucocorticoid receptor. Anti-Glucocorticoid receptor Antibody (5H652) can be used in WB,FCM. |
| Ig Type | IgG |
| Clone | 5H652 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Nucleus. Note=Cytoplasmic in the absence of ligand, nuclear after ligand-binding. Isoform Beta: Nucleus. Note=Localized largely in the nucleus. |
| Tissue Specificity | Widely expressed. In the heart, detected in left and right atria, left and right ventricles, aorta, apex, intraventricular septum, and atrioventricular node as well as whole adult and fetal heart. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. |
| Immunogen | A synthesized peptide: human Glucocorticoid receptor |
| Antigen Species | Human |
| Gene Name | NR3C1 |
| Gene ID | |
| Protein Name | Glucocorticoid receptor |
| Uniprot ID | |
| Function | Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation. |
| Molecular Weight | Theoretical: 86 kDa. Actual: 95 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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