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Anti-CD11b Antibody (5B108)

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Catalog No. TMAC-00649
Alias SLEB6, Neutrophil adherence receptor alpha M subunit, Neutrophil adherence receptor, MO1A, Mo1, alpha subunit, MGC117044, Macrophage antigen alpha polypeptide, Mac-1a, MAC1A, Mac1, alpha subunit, MAC1, MAC 1, Ly-40, Leukocyte adhesion receptor MO1, ITGAM, ITAM_HUMAN, integrin, alpha M (complement component 3 receptor 3 subunit), Integrin subunit alpha M, Integrin beta 2 alpha subunit, Integrin alpha-M, Integrin alpha M chain, Integrin Alpha M, F730045J24Rik, CR3A, CR-3 alpha chain, CR3, CR 3 alpha chain (CR3A), CR 3 alpha chain, Complement receptor type 3, alpha subunit, Complement Component Receptor 3 Alpha, Complement component 3 receptor 3 subunit, Cell surface glycoprotein MAC-1 subunit alpha, CD49d, CD11b/CD18, CD11b, CD11 antigen-like family member B, CD11 antigen like family member B, Antigen CD11b p170, antigen CD11b (p170)

Anti-CD11b Antibody (5B108) is a Rabbit antibody targeting CD11b. Anti-CD11b Antibody (5B108) can be used in WB,ICC,IF,IP,IHC,FCM.

Anti-CD11b Antibody (5B108)

Anti-CD11b Antibody (5B108)

😃Good
Catalog No. TMAC-00649Alias SLEB6, Neutrophil adherence receptor alpha M subunit, Neutrophil adherence receptor, MO1A, Mo1, alpha subunit, MGC117044, Macrophage antigen alpha polypeptide, Mac-1a, MAC1A, Mac1, alpha subunit, MAC1, MAC 1, Ly-40, Leukocyte adhesion receptor MO1, ITGAM, ITAM_HUMAN, integrin, alpha M (complement component 3 receptor 3 subunit), Integrin subunit alpha M, Integrin beta 2 alpha subunit, Integrin alpha-M, Integrin alpha M chain, Integrin Alpha M, F730045J24Rik, CR3A, CR-3 alpha chain, CR3, CR 3 alpha chain (CR3A), CR 3 alpha chain, Complement receptor type 3, alpha subunit, Complement Component Receptor 3 Alpha, Complement component 3 receptor 3 subunit, Cell surface glycoprotein MAC-1 subunit alpha, CD49d, CD11b/CD18, CD11b, CD11 antigen-like family member B, CD11 antigen like family member B, Antigen CD11b p170, antigen CD11b (p170)
Anti-CD11b Antibody (5B108) is a Rabbit antibody targeting CD11b. Anti-CD11b Antibody (5B108) can be used in WB,ICC,IF,IP,IHC,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4987-10 days
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Product Introduction

Bioactivity
Description
Anti-CD11b Antibody (5B108) is a Rabbit antibody targeting CD11b. Anti-CD11b Antibody (5B108) can be used in WB,ICC,IF,IP,IHC,FCM.
SynonymsSLEB6, Neutrophil adherence receptor alpha M subunit, Neutrophil adherence receptor, MO1A, Mo1, alpha subunit, MGC117044, Macrophage antigen alpha polypeptide, Mac-1a, MAC1A, Mac1, alpha subunit, MAC1, MAC 1, Ly-40, Leukocyte adhesion receptor MO1, ITGAM, ITAM_HUMAN, integrin, alpha M (complement component 3 receptor 3 subunit), Integrin subunit alpha M, Integrin beta 2 alpha subunit, Integrin alpha-M, Integrin alpha M chain, Integrin Alpha M, F730045J24Rik, CR3A, CR-3 alpha chain, CR3, CR 3 alpha chain (CR3A), CR 3 alpha chain, Complement receptor type 3, alpha subunit, Complement Component Receptor 3 Alpha, Complement component 3 receptor 3 subunit, Cell surface glycoprotein MAC-1 subunit alpha, CD49d, CD11b/CD18, CD11b, CD11 antigen-like family member B, CD11 antigen like family member B, Antigen CD11b p170, antigen CD11b (p170)
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD11b antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD11b antibody. Counter stained with hematoxylin.
3. ICC staining CD11b in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. Flow cytometric analysis of THP-1 cells with CD11b antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
5. Western blot analysis of CD11b expression in RAW264.7 cell lysate.
Application
Recommended Dose
IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundIntegrin αM, also designated complement component receptor-3 α, CD11b (p170), macrophage antigen a polypeptide, cell surface glycoprotein Mac-1 a subunit, MAC1A, MO1A and ITGAM) is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin αM combines with the Integrin β2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin αM/β2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 170 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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