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Anti-PDHA1 Antibody (3W688)

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Catalog No. TMAB-10125

Anti-PDHA1 Antibody (3W688) is a Rabbit antibody targeting PDHA1. Anti-PDHA1 Antibody (3W688) can be used in WB,IHC-P,IHC-Fr,IF,ICC/IF.

Anti-PDHA1 Antibody (3W688)

Anti-PDHA1 Antibody (3W688)

😃Good
Catalog No. TMAB-10125
Anti-PDHA1 Antibody (3W688) is a Rabbit antibody targeting PDHA1. Anti-PDHA1 Antibody (3W688) can be used in WB,IHC-P,IHC-Fr,IF,ICC/IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1497-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4737-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-PDHA1 Antibody (3W688) is a Rabbit antibody targeting PDHA1. Anti-PDHA1 Antibody (3W688) can be used in WB,IHC-P,IHC-Fr,IF,ICC/IF.
Ig Type
IgG
Clone
3W688
Reactivity
Human,Mouse,Rat
Application
WB
IHC-P
IHC-Fr
IF
ICC/IF
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationMitochondrion matrix.
Tissue SpecificityTestis. Expressed in postmeiotic spermatogenic cells.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase(E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Antigen Details
Immunogen
A synthesized peptide: human PDHA1
Antigen Species
Human
Gene Name
PDHA1
Gene ID
5160
Protein Name
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
Uniprot ID
P08559
Function
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
Chemical Properties
Molecular WeightTheoretical: 43 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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