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Anti-HIF1AN Antibody (9B616)

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Catalog No. TMAC-01820

Anti-HIF1AN Antibody (9B616) is a Rabbit antibody targeting HIF1AN. Anti-HIF1AN Antibody (9B616) can be used in WB,ICC,IHC,FCM.

Anti-HIF1AN Antibody (9B616)

Anti-HIF1AN Antibody (9B616)

😃Good
Catalog No. TMAC-01820
Anti-HIF1AN Antibody (9B616) is a Rabbit antibody targeting HIF1AN. Anti-HIF1AN Antibody (9B616) can be used in WB,ICC,IHC,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4967-10 days
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Product Introduction

Bioactivity
Description
Anti-HIF1AN Antibody (9B616) is a Rabbit antibody targeting HIF1AN. Anti-HIF1AN Antibody (9B616) can be used in WB,ICC,IHC,FCM.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundFactor inhibiting HIF-1 (FIH-1) exists as a homodimer and binds to HIF-1α. Specifically, FIH-1 operates as an asparaginyl hydroxylase. It catalyzes the hydroxylation of the β-carbon of Asparagine residue 803 within the carboxy terminal transactivation domain of HIF-1α. This hydroxylation event blocks the association of HIF-1α with co-activators. FIH-1 also binds to von Hippel-Lindau (VHL) tumor suppressor protein, which represses transcriptional ac-tivity of HIF-1α. In transiently transfected human osteosarcoma cells, FIH-1 localizes to the cytoplasm. The structure of FIH-1 includes a jellyroll-like β-barrel containing ferrous-binding triad residues. The gene encoding human FIH-1 maps to chromosome 10q24.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: human HIF1AN aa 1-200
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 40 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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