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Anti-CTLA4 Antibody (3L241)

😃Good
Catalog No. TMAH-00311
Alias IDDM12, ICOS, GSE, GRD4, CTLA4, CELIAC3, CD152, ALPS5

Anti-CTLA4 Antibody (3L241) is an antibody targeting CTLA4. Anti-CTLA4 Antibody (3L241) can be used in ELISA, IHC.

Anti-CTLA4 Antibody (3L241)

Anti-CTLA4 Antibody (3L241)

😃Good
Catalog No. TMAH-00311Alias IDDM12, ICOS, GSE, GRD4, CTLA4, CELIAC3, CD152, ALPS5
Anti-CTLA4 Antibody (3L241) is an antibody targeting CTLA4. Anti-CTLA4 Antibody (3L241) can be used in ELISA, IHC.
Pack SizePriceAvailabilityQuantity
50 μL$208 7-10 days
100 μL$347 7-10 days
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Product Introduction

Bioactivity
Description
Anti-CTLA4 Antibody (3L241) is an antibody targeting CTLA4. Anti-CTLA4 Antibody (3L241) can be used in ELISA, IHC.
AliasIDDM12, ICOS, GSE, GRD4, CTLA4, CELIAC3, CD152, ALPS5
Ig Type
Rabbit IgG
Clone
3L241
Reactivity
Human
Verified Activity
1. IHC image of TMAH-00311 diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
2. IHC image of TMAH-00311 diluted at 1:100 and staining in paraffin-embedded human lymph node tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
Application
ELISA, IHC
Recommended Dose
IHC:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationCell membrane; Single-pass type I membrane protein. Note=Exists primarily an intracellular antigen whose surface expression is tightly regulated by restricted trafficking to the cell surface and rapid internalization.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundInhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human CTLA4 (CD152)
Antigen Species
Human
Gene ID
1493
Uniprot ID
Biology Area
Immunology, Stem cells
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Sci Citations

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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