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Synonyms: IDDM12, ICOS, GSE, GRD4, CTLA4, CELIAC3, CD152, ALPS5
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $208 | 7-10 days | 7-10 days | |
| 100 μL | $347 | 7-10 days | 7-10 days |
| Description | Anti-CTLA4 Antibody (3L241) is an antibody targeting CTLA4. Anti-CTLA4 Antibody (3L241) can be used in ELISA,IHC. |
| Synonyms | IDDM12, ICOS, GSE, GRD4, CTLA4, CELIAC3, CD152, ALPS5 |
| Ig Type | Rabbit IgG |
| Clone | 3L241 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Note=Exists primarily an intracellular antigen whose surface expression is tightly regulated by restricted trafficking to the cell surface and rapid internalization. |
| Tissue Specificity | Widely expressed with highest levels in lymphoid tissues. Detected in activated T-cells where expression levels are 30- to 50-fold less than CD28, the stimulatory coreceptor, on the cell surface following activation. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human CTLA4 (CD152) |
| Antigen Species | Human |
| Gene Name | CTLA4 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Immunology, Stem cells |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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