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Anti-CTLA4 Antibody (3L241)
😃Good
Catalog No. TMAH-00311
Alias IDDM12, ICOS, GSE, GRD4, CTLA4, CELIAC3, CD152, ALPS5
Anti-CTLA4 Antibody (3L241) is an antibody targeting CTLA4. Anti-CTLA4 Antibody (3L241) can be used in ELISA,IHC.
Anti-CTLA4 Antibody (3L241)
Anti-CTLA4 Antibody (3L241)
😃Good
Catalog No. TMAH-00311Alias IDDM12, ICOS, GSE, GRD4, CTLA4, CELIAC3, CD152, ALPS5
Anti-CTLA4 Antibody (3L241) is an antibody targeting CTLA4. Anti-CTLA4 Antibody (3L241) can be used in ELISA,IHC.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $208 | 7-10 days | 7-10 days | |
| 100 μL | $347 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CTLA4 Antibody (3L241) is an antibody targeting CTLA4. Anti-CTLA4 Antibody (3L241) can be used in ELISA,IHC. |
| Synonyms | IDDM12, ICOS, GSE, GRD4, CTLA4, CELIAC3, CD152, ALPS5 |
| Ig Type | Rabbit IgG |
| Clone | 3L241 |
| Reactivity | Human |
| Verified Activity | 1. IHC image of TMAH-00311 diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. 2. IHC image of TMAH-00311 diluted at 1:100 and staining in paraffin-embedded human lymph node tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| Application | |
| Recommended Dose | IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Note=Exists primarily an intracellular antigen whose surface expression is tightly regulated by restricted trafficking to the cell surface and rapid internalization. |
| Tissue Specificity | Widely expressed with highest levels in lymphoid tissues. Detected in activated T-cells where expression levels are 30- to 50-fold less than CD28, the stimulatory coreceptor, on the cell surface following activation. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human CTLA4 (CD152) |
| Antigen Species | Human |
| Gene Name | CTLA4 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Immunology, Stem cells |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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