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Anti-IMP3 Antibody (8M413)

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Catalog No. TMAB-07688

Anti-IMP3 Antibody (8M413) is a Rabbit antibody targeting IMP3. Anti-IMP3 Antibody (8M413) can be used in WB,ICC/IF,IP,FCM,IHC-P,IHC-Fr,IF.

Anti-IMP3 Antibody (8M413)

Anti-IMP3 Antibody (8M413)

😃Good
Catalog No. TMAB-07688
Anti-IMP3 Antibody (8M413) is a Rabbit antibody targeting IMP3. Anti-IMP3 Antibody (8M413) can be used in WB,ICC/IF,IP,FCM,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4727-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-IMP3 Antibody (8M413) is a Rabbit antibody targeting IMP3. Anti-IMP3 Antibody (8M413) can be used in WB,ICC/IF,IP,FCM,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
8M413
Reactivity
Human
Application
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Cytoplasm. Note=Found in lamellipodia of the leading edge, in the perinuclear region, and beneath the plasma membrane. The subcytoplasmic localization is cell specific and regulated by cell contact and growth. Localized at the connecting piece and the tail of the spermatozoa. Colocalized with CD44 mRNA in RNP granules.
Tissue SpecificityExpressed in fetal liver, fetal lung, fetal kidney, fetal thymus, fetal placenta, fetal follicles of ovary and gonocytes of testis, growing oocytes, spermatogonia and semen (at protein level). Expressed in cervix adenocarcinoma, in testicular, pancreatic and renal-cell carcinomas (at protein level). Expressed ubiquitously during fetal development at 8 and 14 weeks of gestation. Expressed in ovary, testis, brain, placenta, pancreatic cancer tissues and pancreatic cancer cell lines.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundRNA-binding factor that may recruit target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage.
Antigen Details
Immunogen
A synthesized peptide: human IMP 3
Antigen Species
Human
Gene Name
IGF2BP3
Gene ID
Protein Name
Insulin-like growth factor 2 mRNA-binding protein 3
Uniprot ID
Function
RNA-binding protein that act as a regulator of mRNA translation and stability. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binds to sequences in the 3'-UTR of CD44 mRNA.
Chemical Properties
Molecular WeightTheoretical: 64 kDa. Actual: 69 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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