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Anti-IFIH1 Antibody (6Q630)

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Catalog No. TMAB-07509

Anti-IFIH1 Antibody (6Q630) is a Rabbit antibody targeting IFIH1. Anti-IFIH1 Antibody (6Q630) can be used in WB,ICC/IF.

Anti-IFIH1 Antibody (6Q630)

Anti-IFIH1 Antibody (6Q630)

😃Good
Catalog No. TMAB-07509
Anti-IFIH1 Antibody (6Q630) is a Rabbit antibody targeting IFIH1. Anti-IFIH1 Antibody (6Q630) can be used in WB,ICC/IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-IFIH1 Antibody (6Q630) is a Rabbit antibody targeting IFIH1. Anti-IFIH1 Antibody (6Q630) can be used in WB,ICC/IF.
Ig Type
IgG
Clone
6Q630
Reactivity
Human
Application
WB
ICC/IF
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus. May be found in the nucleus, during apoptosis.
Tissue SpecificityWidely expressed, at a low level. Expression is detected at slightly highest levels in placenta, pancreas and spleen and at barely levels in detectable brain, testis and lung.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundInnate immune receptor which acts as a cytoplasmic sensor of viral nucleic acids and plays a major role in sensing viral infection and in the activation of a cascade of antiviral responses including the induction of type I interferons and pro-inflammatory cytokines
Antigen Details
Immunogen
A synthesized peptide: human MDA5
Antigen Species
Human
Gene Name
IFIH1
Gene ID
64135
Protein Name
Interferon-induced helicase C domain-containing protein 1
Uniprot ID
Q9BYX4
Function
RNA helicase that, through its ATP-dependent unwinding of RNA, may function to promote message degradation by specific RNases. Seems to have growth suppressive properties. Involved in innate immune defense against viruses. Upon interaction with intracellular dsRNA produced during viral replication, triggers a transduction cascade involving MAVS/IPS1, which results in the activation of NF-kappa-B, IRF3 and IRF7 and the induction of the expression of antiviral cytokines such as IFN-beta and RANTES (CCL5). ATPase activity is specifically induced by dsRNA. Essential for the production of interferons in response to picornaviruses.
Chemical Properties
Molecular WeightTheoretical: 117 kDa. Actual: 117 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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