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NCGC00238624 is a selective inhibitor of galactokinase (GALK1), exhibiting IC50 values of 7.69 μM for human recombinant GALK1 and 13.67 μM for mouse recombinant GALK1. At a concentration of 10 μM, NCGC00238624 shows no activity against GALK2 or other kinases. This compound can be used for research on classic galactosemia.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks | 10-14 weeks |
| Description | NCGC00238624 is a selective inhibitor of galactokinase (GALK1), exhibiting IC50 values of 7.69 μM for human recombinant GALK1 and 13.67 μM for mouse recombinant GALK1. At a concentration of 10 μM, NCGC00238624 shows no activity against GALK2 or other kinases. This compound can be used for research on classic galactosemia. |
| Molecular Weight | 382.804 |
| Formula | C18H15ClN6O2 |
| Cas No. | 2768230-55-1 |
| Smiles | O=C1C=2[C@@H](N=C(NC3=NC=4C(O3)=CC=CC4)NC2CCC1)C=5C(Cl)=CNN5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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