Clusterin Protein, Mouse, Recombinant (His) V2

Name: Clusterin Protein, Mouse, Recombinant (His) V2
Brand: TargetMol
SKU: TMPY-01694U
Rating: 4.5 (1 reviews)

(Synonyms: Sugp-2, SP-40, Sgp-2, Sgp2, D14Ucla3, clusterin, Cli, ApoJ, AI893575) Copy Product Info

Synonyms: Sugp-2, SP-40, Sgp-2, Sgp2, D14Ucla3, clusterin, Cli, ApoJ, AI893575

Catalog No. TMPY-01694U Copy Product Info

Clusterin Protein, Mouse, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is Q06890.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$42	7-10 days	7-10 days
10 µg	$65	7-10 days	7-10 days
20 µg	$98	7-10 days	7-10 days
50 µg	$197	7-10 days	7-10 days
100 µg	$329	7-10 days	7-10 days
200 µg	$583	7-10 days	7-10 days
500 µg	$1,230	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it.
Description	Clusterin Protein, Mouse, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is Q06890.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-His
Accession Number	Q06890
Construction	Glu22-Glu448
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Sugp-2, SP-40, Sgp-2, Sgp2, D14Ucla3, clusterin, Cli, ApoJ, AI893575
Research Background	Clusterin (CLU) is a stress-activated, ATP-independent molecular chaperone, normally secreted from cells, that is up-regulated in Alzheimer disease and in many cancers. It plays important roles in protein homeostasis/proteostasis, inhibition of cell death pathways, and modulation of pro-survival signalling and transcriptional networks. Changes in the CLU gene locus are highly associated with Alzheimer disease, and many therapy-resistant cancers over-express CLU.

Chemical Properties

Molecular Weight

50.4 kDa (Predicted); 35-40 kDa and 43-50 kDa (due to autocatalytic cleavage)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.