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Anti-HDAC7 Antibody (3G941)
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Catalog No. TMAC-01786
Alias HDAC 7
Anti-HDAC7 Antibody (3G941) is a Rabbit antibody targeting HDAC7. Anti-HDAC7 Antibody (3G941) can be used in WB,FCM.
Anti-HDAC7 Antibody (3G941)
Anti-HDAC7 Antibody (3G941)
😃Good
Catalog No. TMAC-01786Alias HDAC 7
Anti-HDAC7 Antibody (3G941) is a Rabbit antibody targeting HDAC7. Anti-HDAC7 Antibody (3G941) can be used in WB,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-HDAC7 Antibody (3G941) is a Rabbit antibody targeting HDAC7. Anti-HDAC7 Antibody (3G941) can be used in WB,FCM. |
| Synonyms | HDAC 7 |
| Ig Type | IgG |
| Clone | 3G941 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of HDAC7 on different lysates using anti-HDAC7 antibody at 1/1,000 dilution. Positive control: Lane 1: A549, Lane 2: Human brain. 2. Flow cytometric analysis of K562 cells with HDAC7 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| Application | |
| Recommended Dose | WB: 1:1000-2000; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBP-associated factor), p300/CBP, HAT1, and the TFIID subunit TAF II p250. Mammalian HDAC7 is a histone deacetylase that interacts with the adaptor mSin3A. The interaction of HDAC7 with mSin3A suggests the association of multiple repression complexes of transcription factors. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 109/99 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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