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Anti-MAP4K4 Antibody (7A976)
Catalog No. TMAB-08581 Copy Product Info
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Anti-MAP4K4 Antibody (7A976) is a Rabbit antibody targeting MAP4K4. Anti-MAP4K4 Antibody (7A976) can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Anti-MAP4K4 Antibody (7A976)
Copy Product Info🥰Excellent
Catalog No. TMAB-08581
Anti-MAP4K4 Antibody (7A976) is a Rabbit antibody targeting MAP4K4. Anti-MAP4K4 Antibody (7A976) can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Anti-MAP4K4 Antibody
(7A976)
(7A976)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-MAP4K4 Antibody (7A976) is a Rabbit antibody targeting MAP4K4. Anti-MAP4K4 Antibody (7A976) can be used in IHC-P,IHC-Fr,ICC/IF,IF. |
| Ig Type | IgG |
| Clone | 7A976 |
| Reactivity | Human |
| Verified Activity | 1. Cell line: HepG2 Fixative: 4% Paraformaldehyde Permeabilization: 0.1% TritonX-100 Primary ab dilution: 1:50 Primary incubation condition: 4°C overnight Secondary ab: Goat Anti-Rabbit IgG Nuclear counter stain: DAPI (Blue) Comment: Color green is the positive signal for TMAB-08581 2. Tissue: Human prostate Section type: Formalin fixed & Paraffin-embedded section Retrieval method: High temperature and high pressure Retrieval buffer: Tris/EDTA buffer, pH 9.0 Primary ab dilution: 1:50 Primary ab incubation condition: 1 hour at room temperature Counter stain: Hematoxylin Comment: Color brown is the positive signal for TMAB-08581 |
| Application | |
| Recommended Dose | IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. |
| Tissue Specificity | Appears to be ubiquitous. Expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain. Isoform 4 is predominant in the liver, skeletal muscle and placenta. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human MAP4K4 |
| Antigen Species | Human |
| Gene Name | MAP4K4 |
| Gene ID | |
| Protein Name | Mitogen-activated protein kinase kinase kinase kinase 4 |
| Uniprot ID | |
| Function | Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322. |
| Molecular Weight | Theoretical: 142 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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