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Anti-IL-12B Antibody (1Q82)

😃Good
Catalog No. TMAH-00609
Alias NKSF2, NKSF, interleukin 12B, IMD29, IMD28, IL-12B, IL12 p40, CLMF2, CLMF

Anti-IL-12B Antibody (1Q82) is an antibody targeting IL-12B. Anti-IL-12B Antibody (1Q82) can be used in ELISA, FCM.

Anti-IL-12B Antibody (1Q82)

Anti-IL-12B Antibody (1Q82)

😃Good
Catalog No. TMAH-00609Alias NKSF2, NKSF, interleukin 12B, IMD29, IMD28, IL-12B, IL12 p40, CLMF2, CLMF
Anti-IL-12B Antibody (1Q82) is an antibody targeting IL-12B. Anti-IL-12B Antibody (1Q82) can be used in ELISA, FCM.
Pack SizePriceAvailabilityQuantity
50 μL$209 7-10 days
100 μL$347 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Recombinant Rabbit Monoclonal

Application: ELISA, FCM

Reactivity: Human
AliasNKSF2, NKSF, interleukin 12B, IMD29, IMD28, IL-12B, IL12 p40, CLMF2, CLMF
Ig Type
Rabbit IgG
Clone
1Q82
Reactivity
Human
Verified Activity
Overlay Peak curve showing A549 cells stained with TMAH-00609 (red line) at 1:50. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1µg/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was rabbit IgG (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed.
Application
ELISA, FCM
Recommended Dose
FCM:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationSecreted.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundCytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human IL12B
Antigen Species
Human
Gene ID
3593
Uniprot ID
Biology Area
Cancer, Immunology
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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