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Anti-ABCB11 Antibody (1N110)

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Catalog No. TMAB-02144

Anti-ABCB11 Antibody (1N110) is a Rabbit antibody targeting ABCB11. Anti-ABCB11 Antibody (1N110) can be used in WB,IHC-P,IHC-Fr,IF.

Anti-ABCB11 Antibody (1N110)

Anti-ABCB11 Antibody (1N110)

😃Good
Catalog No. TMAB-02144
Anti-ABCB11 Antibody (1N110) is a Rabbit antibody targeting ABCB11. Anti-ABCB11 Antibody (1N110) can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1497-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4727-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-ABCB11 Antibody (1N110) is a Rabbit antibody targeting ABCB11. Anti-ABCB11 Antibody (1N110) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
1N110
Reactivity
Human (predicted:Mouse)
Application
Recommended Dose
WB: 1:500-1000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Multi-pass membrane protein.
Tissue SpecificityExpressed predominantly, if not exclusively in the liver, where it was further localized to the canalicular microvilli and to subcanalicular vesicles of the hepatocytes by in situ.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008]
Antigen Details
Gene Name
ABCB11
Gene ID
Protein Name
Bile salt export pump
Function
Involved in the ATP-dependent secretion of bile salts into the canaliculus of hepatocytes.
Chemical Properties
Molecular WeightTheoretical: 146 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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