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Anti-ABCB11 Antibody (1N110) (Synonyms: SPGP, PGY4, PFIC-2, PFIC2, EC:7.6.2.-, BSEP, BRIC2, Bile salt exp...)
Catalog No. TMAB-02144 Copy Product Info
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Anti-ABCB11 Antibody (1N110) is a Rabbit antibody targeting ABCB11. Anti-ABCB11 Antibody (1N110) can be used in WB,IHC-P,IHC-Fr,IF.
Anti-ABCB11 Antibody (1N110)
Copy Product Info🥰Excellent
Catalog No. TMAB-02144
Synonyms SPGP, PGY4, PFIC-2, PFIC2, EC:7.6.2.-, BSEP, BRIC2, Bile salt export pump, ATP-binding cassette sub-family B member 11, ABCBB_HUMAN, ABC16
Anti-ABCB11 Antibody (1N110) is a Rabbit antibody targeting ABCB11. Anti-ABCB11 Antibody (1N110) can be used in WB,IHC-P,IHC-Fr,IF.
Anti-ABCB11 Antibody
(1N110)
(1N110)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-ABCB11 Antibody (1N110) is a Rabbit antibody targeting ABCB11. Anti-ABCB11 Antibody (1N110) can be used in WB,IHC-P,IHC-Fr,IF. |
| Synonyms | SPGP, PGY4, PFIC-2, PFIC2, EC:7.6.2.-, BSEP, BRIC2, Bile salt export pump, ATP-binding cassette sub-family B member 11, ABCBB_HUMAN, ABC16 |
| Ig Type | IgG |
| Clone | 1N110 |
| Reactivity | Human (predicted:Mouse) |
| Verified Activity | 1. Blocking buffer: 5% NFDM/TBST Primary ab dilution: 1:1000 Primary ab incubation condition: 2 hours at room temperature Secondary ab: Goat Anti-Rabbit IgG H&L (HRP) Lysate: 1: Jurkat, 2: HepG2, 3: A549, 4: LNCaP, 5: Mouse liver Protein loading quantity: 20 μg Exposure time: 60 s Predicted MW: 146 kDa Observed MW: 146 kDa 2. Tissue: Human liver Section type: Formalin fixed & Paraffin-embedded section Retrieval method: High temperature and high pressure Retrieval buffer: Tris/EDTA buffer, pH 9.0 Primary ab dilution: 1:500 Primary ab incubation condition: 1 hour at room temperature Secondary ab: SP Kit (Rabbit) Counter stain: Hematoxylin (Blue) Comment: Color brown is the positive signal for TMAB-02144 |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Multi-pass membrane protein. |
| Tissue Specificity | Expressed predominantly, if not exclusively in the liver, where it was further localized to the canalicular microvilli and to subcanalicular vesicles of the hepatocytes by in situ. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008] |
| Gene Name | ABCB11 |
| Gene ID | |
| Protein Name | Bile salt export pump |
| Function | Involved in the ATP-dependent secretion of bile salts into the canaliculus of hepatocytes. |
| Molecular Weight | Theoretical: 146 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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