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Anti-Adenylosuccinate Lyase Antibody (8T693)
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Catalog No. TMAY-01825
Alias ASL, ASASE, AMPS, adenylosuccinate lyase
Anti-Adenylosuccinate Lyase Antibody (8T693) is a Mouse antibody targeting Adenylosuccinate Lyase. Anti-Adenylosuccinate Lyase Antibody (8T693) can be used in ICC/IF.
Anti-Adenylosuccinate Lyase Antibody (8T693)
Anti-Adenylosuccinate Lyase Antibody (8T693)
😃Good
Catalog No. TMAY-01825Alias ASL, ASASE, AMPS, adenylosuccinate lyase
Anti-Adenylosuccinate Lyase Antibody (8T693) is a Mouse antibody targeting Adenylosuccinate Lyase. Anti-Adenylosuccinate Lyase Antibody (8T693) can be used in ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Recombinant Mouse Monoclonal Application: ICC/IF Reactivity: Human |
| Alias | ASL, ASASE, AMPS, adenylosuccinate lyase |
| Ig Type | Mouse IgG1 |
| Clone | 8T693 |
| Reactivity | Human |
| Verified Activity | Immunofluorescence staining of His-ADSL in HeLa cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS,blocked with 10% serum, and incubated with mouse anti-Human His-ADSL monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-mouse IgG secondary antibody (green) and counterstained with DAPI (blue).Positive staining was localized to Cytoplasm. |
| Application | ICC/IF |
| Recommended Dose | ICC-IF: 1:20-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This product is a recombinant monoclonal antibody expressed from HEK293 cells. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Adenylosuccinate lyase, also known as adenylosuccinase, ADSL or ASL, is an enzyme implicated in the reaction of adenylosuccinat converting to AMP and fumarate as part of the purine nucleotide cycle. The two substates of adenylosuccinate lyase (ADSL) are dephosphorylated derivatives of SAICA ribotide (SAICAR) and adenylosuccinate (S-AMP), which catalyzes an important reaction in the de novo pathway of purine biosynthesis. ADSL catalyzes two distinct reactions in the synthesis of purine nucleotides, both of which involve the _-elimination of fumarate to produce either aminoimidazole carboxamide ribotide from SAICAR or AMP from S-AMP. The Adenylosuccinate lyase deficiency is a rare autosomal recessive metabolic disorder characterized by the present of SAICA riboside and succinyladenosine (S-Ado). ADSL defect in different patients is often caused by different mutations to the enzyme. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Adenylosuccinate Lyase Protein (TMPY-02552) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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