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Anti-SMN1 Antibody (4M550)

😃Good
Catalog No. TMAB-12977

Anti-SMN1 Antibody (4M550) is a Rabbit antibody targeting SMN1. Anti-SMN1 Antibody (4M550) can be used in WB,IHC-P,IHC-Fr,IP,IF.

Anti-SMN1 Antibody (4M550)

Anti-SMN1 Antibody (4M550)

😃Good
Catalog No. TMAB-12977
Anti-SMN1 Antibody (4M550) is a Rabbit antibody targeting SMN1. Anti-SMN1 Antibody (4M550) can be used in WB,IHC-P,IHC-Fr,IP,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-SMN1 Antibody (4M550) is a Rabbit antibody targeting SMN1. Anti-SMN1 Antibody (4M550) can be used in WB,IHC-P,IHC-Fr,IP,IF.
Ig Type
IgG
Clone
4M550
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IP: 1:20-50; IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus, gem. Note=Localized in subnuclear structures next to coiled bodies, called Gemini of Cajal bodies (Gems).
Tissue SpecificityExpressed in a wide variety of tissues. Expressed at high levels in brain, kidney and liver, moderate levels in skeletal and cardiac muscle, and low levels in fibroblasts and lymphocytes. Also seen at high levels in spinal cord. Present in osteoclasts and mononuclear cells (at protein level).
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundThe SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP.
Antigen Details
Immunogen
A synthesized peptide: human SMN1
Antigen Species
Human
Gene Name
SMN1
Gene ID
Protein Name
Survival motor neuron protein
Uniprot ID
Function
The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs.
Chemical Properties
Molecular WeightTheoretical: 32 kDa. Actual: 36 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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