Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-ERCC8 Antibody (1V748)
Catalog No. TMAB-05660 Copy Product Info
🥰Excellent
Anti-ERCC8 Antibody (1V748) is a Rabbit antibody targeting ERCC8. Anti-ERCC8 Antibody (1V748) can be used in WB,IP.
Anti-ERCC8 Antibody (1V748)
Copy Product Info🥰Excellent
Catalog No. TMAB-05660
Anti-ERCC8 Antibody (1V748) is a Rabbit antibody targeting ERCC8. Anti-ERCC8 Antibody (1V748) can be used in WB,IP.
Anti-ERCC8 Antibody
(1V748)
(1V748)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Resource Download
Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-ERCC8 Antibody (1V748) is a Rabbit antibody targeting ERCC8. Anti-ERCC8 Antibody (1V748) can be used in WB,IP. |
| Ig Type | IgG |
| Clone | 1V748 |
| Reactivity | Human |
| Verified Activity | 25 μg total protein per lane of various lysates (see on figure) probed with ERCC8 monoclonal antibody, unconjugated (TMAB-05660) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000; IP: 1:20-50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Substrate-recognition component of the CSA complex, a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, involved in transcription-coupled nucleotide excision repair. The CSA complex (DCX(ERCC8) complex) promotes the ubiquitination and subsequent proteasomal degradation of ERCC6 in a UV-dependent manner; ERCC6 degradation is essential for the recovery of RNA synthesis after transcription-coupled repair. |
| Immunogen | A synthesized peptide: human ERCC8 |
| Antigen Species | Human |
| Gene Name | ERCC8 |
| Gene ID | |
| Protein Name | DNA excision repair protein ERCC-8 |
| Uniprot ID | |
| Function | Substrate-recognition component of the CSA complex, a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, involved in transcription-coupled nucleotide excision repair. The CSA complex (DCX(ERCC8) complex) promotes the ubiquitination and subsequent proteasomal degradation of ERCC6 in a UV-dependent manner; ERCC6 degradation is essential for the recovery of RNA synthesis after transcription-coupled repair. It is required for the recruitement of XAB2, HMGN1 and TCEA1/TFIIS to a transcription-coupled repair complex which removes RNA polymerase II-blocking lesions from the transcribed strand of active genes. |
| Molecular Weight | Theoretical: 44 kDa. Actual: 44 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
Preview
Related Tags: buy Anti-ERCC8 Antibody (1V748) | purchase Anti-ERCC8 Antibody (1V748) | Anti-ERCC8 Antibody (1V748) cost | order Anti-ERCC8 Antibody (1V748) | Anti-ERCC8 Antibody (1V748) molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.