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Anti-CD79B Antibody (5M778) is an antibody targeting CD79B. Anti-CD79B Antibody (5M778) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $208 | 7-10 days | |
100 μL | $348 | 7-10 days |
Description | Antibody Type: Recombinant Monoclonal Application: ELISA Reactivity: Human |
Alias | Ig-β, Ig-beta, IGBAGM6, IGB, CD79b molecule, CD79B, B29 |
Ig Type | hIgG1 |
Clone | 5M778 |
Reactivity | Human |
Verified Activity | 1. The Binding Activity of Human CD79B with Anti-CD79B recombinant antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD79A at 2 μg/mL can bind Anti-CD79B recombinant antibody. The EC50 is 3.214-3.642 ng/mL. 2. The Binding Activity of Human CD79A&CD79B with Anti-CD79B recombinant antibody Activity:Measured by its binding ability in a functional ELISA. Immobilized Human CD79A&CD79B at 2 μg/mL can bind Anti-CD79B recombinant antibody. The EC50 is 14.85-17.47 ng/mL. 3. The Binding Activity of Human CD79B with Anti-CD79B recombinant antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD79B at 2 μg/mL can bind Anti-CD79B recombinant antibody. The EC50 is 31.97-35.69 ng/mL. 4. Untransfected HEK-293T cells (green line) and transfected Human CD79B HEK-293T stable cells (red line) were stained with anti-CD79B antibody(TMAH-00222) (2µg/1*10^6 cells), washed and then followed by APC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry. 5. Untransfected HEK-293T cells (green line) and transfected Human CD79A&CD79B HEK-293T stable cells (red line) were stained with anti-CD79B antibody(TMAH-00222) (2µg/1*10^6 cells), washed and then followed by APC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry. |
Application | ELISA |
Recommended Dose | ELISA:1:5000-1:50000. |
Antibody Type | Monoclonal |
Subcellular Localization | Cell membrane; Single-pass type I membrane protein. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
Research Background | Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: Human CD79B Protein |
Antigen Species | Human |
Gene ID | 974 |
Uniprot ID | |
Biology Area | Immunology |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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