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Anti-INPP4B Antibody (6A543)

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Catalog No. TMAB-07716

Anti-INPP4B Antibody (6A543) is a Rabbit antibody targeting INPP4B. Anti-INPP4B Antibody (6A543) can be used in IF, IHC-Fr, IHC-P, WB.

Anti-INPP4B Antibody (6A543)

Anti-INPP4B Antibody (6A543)

Copy Product Info
😃Good
Catalog No. TMAB-07716
Anti-INPP4B Antibody (6A543) is a Rabbit antibody targeting INPP4B. Anti-INPP4B Antibody (6A543) can be used in IF, IHC-Fr, IHC-P, WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1497-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-INPP4B Antibody (6A543) is a Rabbit antibody targeting INPP4B. Anti-INPP4B Antibody (6A543) can be used in IF, IHC-Fr, IHC-P, WB.
Ig Type
IgG
Clone
6A543
Reactivity
Human,Mouse
Verified Activity
1. 25 ug total protein per lane of various lysates (see on figure) probed with INPP4B monoclonal antibody, unconjugated (TMAB-07716) at 1: 1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
2. Paraformaldehyde-fixed, paraffin embedded Human Lung Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with INPP4B Monoclonal Antibody, Unconjugated (TMAB-07716) at 1:200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L-HRP and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded Human Skeletal muscle; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with INPP4B Monoclonal Antibody, Unconjugated (TMAB-07716) at 1:200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L-HRP and DAB staining.
4. Paraformaldehyde-fixed, paraffin embedded Human Breast Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with INPP4B Monoclonal Antibody, Unconjugated (TMAB-07716) at 1:200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L-HRP and DAB staining.
Application
Recommended Dose
IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; WB=1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Tissue SpecificityWidely expressed with highest levels occurring in the skeletal muscle and heart.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundCatalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 3,4-trisphosphate. Plays a role in the late stages of macropinocytosis by dephosphorylating phosphatidylinositol 3,4-bisphosphate in membrane ruffles.The lipid phosphatase activity is critical for tumor suppressor function. Antagonizes the PI3K-AKT/PKB signaling pathway by dephosphorylating phosphoinositides and thereby modulating cell cycle progression and cell survival
Antigen Details
Immunogen
A synthesized peptide: human INPP4B
Antigen Species
Human
Gene Name
INPP4B
Gene ID
Protein Name
Inositol polyphosphate 4-phosphatase type II
Uniprot ID
Function
Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 1,4-bisphosphate.
Chemical Properties
Molecular WeightTheoretical: 105 kDa. Actual: 107 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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