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Anti-PARP2 Antibody (2O416)

Catalog No. TMAB-09996 Copy Product Info
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Anti-PARP2 Antibody (2O416) is a Rabbit antibody targeting PARP2. Anti-PARP2 Antibody (2O416) can be used in WB,ICC/IF,FCM.

Anti-PARP2 Antibody (2O416)

Copy Product Info
🥰Excellent
Catalog No. TMAB-09996

Anti-PARP2 Antibody (2O416) is a Rabbit antibody targeting PARP2. Anti-PARP2 Antibody (2O416) can be used in WB,ICC/IF,FCM.

Anti-PARP2 Antibody
(2O416)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1507-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-PARP2 Antibody (2O416) is a Rabbit antibody targeting PARP2. Anti-PARP2 Antibody (2O416) can be used in WB,ICC/IF,FCM.
Ig Type
IgG
Clone
2O416
Reactivity
Human (predicted:Mouse,Rat)
Verified Activity
25 μg total protein per lane of various lysates (see on figure) probed with PARP2 monoclonal antibody, unconjugated (TMAB-09996) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
Tissue SpecificityWidely expressed, mainly in actively dividing tissues. The highest levels are in the brain, heart, pancreas, skeletal muscle and testis; also detected in kidney, liver, lung, placenta, ovary and spleen; levels are low in leukocytes, colon, small intestine, prostate and thymus.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundPoly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair.Mediates glutamate, aspartate or serine ADP-ribosylation of proteins: the ADP-D-ribosyl group of NAD+ is transferred to the acceptor carboxyl group of target residues and further ADP-ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units.
Antigen Details
Immunogen
A synthesized peptide: human PARP 2
Antigen Species
Human
Gene Name
PARP2
Gene ID
Protein Name
Poly [ADP-ribose] polymerase 2
Uniprot ID
Function
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Chemical Properties
Molecular WeightTheoretical: 66 kDa. Actual: 66 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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