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Anti-Mucin-4/MUC4 Antibody (8K130)
😃Good
Catalog No. TMAC-02683
Alias Testis mucin, Pancreatic adenocarcinoma mucin, Mucin-4, MUC-4, Muc4, Ascites sialoglycoprotein (ASGP)
Anti-Mucin-4/MUC4 Antibody (8K130) is a Rabbit antibody targeting Mucin-4/MUC4. Anti-Mucin-4/MUC4 Antibody (8K130) can be used in FCM,IHC,WB.
Anti-Mucin-4/MUC4 Antibody (8K130)
Anti-Mucin-4/MUC4 Antibody (8K130)
😃Good
Catalog No. TMAC-02683Alias Testis mucin, Pancreatic adenocarcinoma mucin, Mucin-4, MUC-4, Muc4, Ascites sialoglycoprotein (ASGP)
Anti-Mucin-4/MUC4 Antibody (8K130) is a Rabbit antibody targeting Mucin-4/MUC4. Anti-Mucin-4/MUC4 Antibody (8K130) can be used in FCM,IHC,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Mucin-4/MUC4 Antibody (8K130) is a Rabbit antibody targeting Mucin-4/MUC4. Anti-Mucin-4/MUC4 Antibody (8K130) can be used in FCM,IHC,WB. |
| Synonyms | Testis mucin, Pancreatic adenocarcinoma mucin, Mucin-4, MUC-4, Muc4, Ascites sialoglycoprotein (ASGP) |
| Ig Type | IgG |
| Clone | 8K130 |
| Reactivity | Human,Rat |
| Application | |
| Recommended Dose | WB: 1:500; IHC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Mucins are a group of high molecular weight glycoproteins consisting of a mucin core protein and O-linked carbohydrates. Mucin 4, a membrane-bound mucin, is the human homolog of the rat sialomucin complex (SMC). Mucin 4 protein consists of Mucin 4α, a large amino mucin type subunit, and Mucin 4β, a transmembrane subunit containing three EGF-like domains. The Mucin 4 gene is the predominant mucin gene expressed in the normal urothelium and is also expressed in several normal tissues such as trachea, lung and testis. Dysregulation of Mucin 4 results in high levels of expression in pancreatic tumors and tumor cell lines. Induction of Mucin 4 in pancreatic carcinoma by all-trans-retinoic acid is mediated through the retinoic acid receptor-α signaling pathway. TGFβ2 serves as an interim mediator of this regulated expression. Alternative splicing in the 3'-end of the Mucin 4 gene generates at least 12 splice variants, which are characterized as two distinct types, a secreted type and a membrane-associated type. Mucin 4 protein acts as a heterodimeric bifunctional cell-surface glycoprotein and forms thick mucous effusion in the diseased middle ear. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 120 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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