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Anti-HMGB1 Antibody (3V165)
😃Good
Catalog No. TMAB-07183
Anti-HMGB1 Antibody (3V165) is a Rabbit antibody targeting HMGB1. Anti-HMGB1 Antibody (3V165) can be used in WB,IHC-P,IF,FCM,IHC-Fr,ICC/IF.
Anti-HMGB1 Antibody (3V165)
Anti-HMGB1 Antibody (3V165)
😃Good
Catalog No. TMAB-07183
Anti-HMGB1 Antibody (3V165) is a Rabbit antibody targeting HMGB1. Anti-HMGB1 Antibody (3V165) can be used in WB,IHC-P,IF,FCM,IHC-Fr,ICC/IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-HMGB1 Antibody (3V165) is a Rabbit antibody targeting HMGB1. Anti-HMGB1 Antibody (3V165) can be used in WB,IHC-P,IF,FCM,IHC-Fr,ICC/IF. |
| Ig Type | IgG |
| Clone | 3V165 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:1000-5000; IHC-P: 1:200-1000; IF: 1:200-1000; FCM: 1μg/Test; IHC-Fr: 1:200-1000; ICC/IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Chromosome. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | High Mobility Group Box-1 (HMGB1) is a cytokine implicated in the pathogenesis of rheumatoid arthritis (RA) and other inflammatory diseases. The cholinergic anti-inflammatory pathway, a vagus nerve dependent mechanism, inhibits HMGB1 release in experimental disease models |
| Immunogen | A synthesized peptide: human HMGB1 |
| Antigen Species | Human |
| Gene Name | HMGB1 |
| Gene ID | |
| Protein Name | High mobility group protein B1 |
| Uniprot ID | |
| Function | DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells. |
| Molecular Weight | Theoretical: 25 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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