Shopping Cart
Remove All
Your shopping cart is currently empty
Oportuzumab
Copy Product Info
🥰Excellent
Synonyms:
Catalog No. T9901A-1243 Copy Product Info
🥰Excellent
Oportuzumab (commonly studied as Oportuzumab monatox or Vicineum) is a humanized recombinant fusion protein specifically targeting the epithelial cell adhesion molecule (EpCAM/CD326). It consists of a single-chain variable fragment (scFv) directed against EpCAM covalently linked to a truncated, modified fragment of Pseudomonas exotoxin A (ETA). EpCAM is significantly overexpressed in epithelial-derived malignancies, particularly bladder cancer. Oportuzumab binds specifically to the EpCAM protein on the tumor cell surface and is internalized via endocytosis, after which the toxin payload is released into the cytoplasm. The toxin irreversibly inhibits eukaryotic elongation factor 2 (eEF-2), thereby blocking protein synthesis and ultimately inducing apoptosis in cancer cells.
Cas No. 945228-48-8
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $318 | Inquiry | Inquiry | |
| 5 mg | $998 | Inquiry | Inquiry | |
| 10 mg | $1,590 | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Oportuzumab (commonly studied as Oportuzumab monatox or Vicineum) is a humanized recombinant fusion protein specifically targeting the epithelial cell adhesion molecule (EpCAM/CD326). It consists of a single-chain variable fragment (scFv) directed against EpCAM covalently linked to a truncated, modified fragment of Pseudomonas exotoxin A (ETA). EpCAM is significantly overexpressed in epithelial-derived malignancies, particularly bladder cancer. Oportuzumab binds specifically to the EpCAM protein on the tumor cell surface and is internalized via endocytosis, after which the toxin payload is released into the cytoplasm. The toxin irreversibly inhibits eukaryotic elongation factor 2 (eEF-2), thereby blocking protein synthesis and ultimately inducing apoptosis in cancer cells. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | EpCAM/TROP1/CD326 |
| Cas No. | 945228-48-8 |
| Isotype | IgG1 |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
Calculator
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: Oportuzumab chemical structure
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.