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Anti-PMAIP1 Antibody (1B633)

😃Good
Catalog No. TMAB-11573

Anti-PMAIP1 Antibody (1B633) is a Rabbit antibody targeting PMAIP1. Anti-PMAIP1 Antibody (1B633) can be used in WB.

Anti-PMAIP1 Antibody (1B633)

Anti-PMAIP1 Antibody (1B633)

😃Good
Catalog No. TMAB-11573
Anti-PMAIP1 Antibody (1B633) is a Rabbit antibody targeting PMAIP1. Anti-PMAIP1 Antibody (1B633) can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-PMAIP1 Antibody (1B633) is a Rabbit antibody targeting PMAIP1. Anti-PMAIP1 Antibody (1B633) can be used in WB.
Ig Type
IgG
Clone
1B633
Reactivity
Human
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationMitochondrion.
Tissue SpecificityHighly expressed in adult T-cell leukemia cell line.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundNoxa is a pro-apoptotic Bcl-2 family protein that contains a single Bcl-2 homology (BH3) domain. Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1.
Antigen Details
Immunogen
A synthesized peptide: human PMAIP1
Antigen Species
Human
Gene Name
PMAIP1
Gene ID
Protein Name
Phorbol-12-myristate-13-acetate-induced protein 1
Uniprot ID
Function
Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
Chemical Properties
Molecular WeightTheoretical: 6 kDa. Actual: 16 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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