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Anti-PMAIP1 Antibody (1B633)
Catalog No. TMAB-11573 Copy Product Info
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Anti-PMAIP1 Antibody (1B633) is a Rabbit antibody targeting PMAIP1. Anti-PMAIP1 Antibody (1B633) can be used in WB.
Anti-PMAIP1 Antibody (1B633)
Copy Product Info🥰Excellent
Catalog No. TMAB-11573
Anti-PMAIP1 Antibody (1B633) is a Rabbit antibody targeting PMAIP1. Anti-PMAIP1 Antibody (1B633) can be used in WB.
Anti-PMAIP1 Antibody
(1B633)
(1B633)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-PMAIP1 Antibody (1B633) is a Rabbit antibody targeting PMAIP1. Anti-PMAIP1 Antibody (1B633) can be used in WB. |
| Ig Type | IgG |
| Clone | 1B633 |
| Reactivity | Human |
| Verified Activity | Western blot analysis of Jurkat cell lysate;. Using Noxa (TMAB-11573) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion. |
| Tissue Specificity | Highly expressed in adult T-cell leukemia cell line. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Noxa is a pro-apoptotic Bcl-2 family protein that contains a single Bcl-2 homology (BH3) domain. Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. |
| Immunogen | A synthesized peptide: human PMAIP1 |
| Antigen Species | Human |
| Gene Name | PMAIP1 |
| Gene ID | |
| Protein Name | Phorbol-12-myristate-13-acetate-induced protein 1 |
| Uniprot ID | |
| Function | Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1. |
| Molecular Weight | Theoretical: 6 kDa. Actual: 16 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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