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Anti-GUCY2C Antibody (4L52) (Synonyms: STAR, STA receptor, MUCIL, GUCY2C, GUC2CEC 4.6.1.2, GUC2C, Guanylyl...)

Catalog No. TMAH-00523 Copy Product Info
Purity: 95%
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Anti-GUCY2C Antibody (4L52) is an antibody targeting GUCY2C. Anti-GUCY2C Antibody (4L52) can be used in ELISA,FCM.

Anti-GUCY2C Antibody (4L52)

Copy Product Info
🥰Excellent
Catalog No. TMAH-00523
Synonyms STAR, STA receptor, MUCIL, GUCY2C, GUC2CEC 4.6.1.2, GUC2C, Guanylyl cyclase C, GC-C, GCC, EC 4.6.1, DIAR6

Anti-GUCY2C Antibody (4L52) is an antibody targeting GUCY2C. Anti-GUCY2C Antibody (4L52) can be used in ELISA,FCM.

Anti-GUCY2C Antibody
(4L52)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2077-10 days7-10 days
100 μL$3477-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Anti-GUCY2C Antibody (4L52) is an antibody targeting GUCY2C. Anti-GUCY2C Antibody (4L52) can be used in ELISA,FCM.
SynonymsSTAR, STA receptor, MUCIL, GUCY2C, GUC2CEC 4.6.1.2, GUC2C, Guanylyl cyclase C, GC-C, GCC, EC 4.6.1, DIAR6
Ig Type
Human IgG1
Clone
4L52
Reactivity
Human
Verified Activity
1. The Binding Activity of Human GUCY2C with Anti-GUCY2C recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human GUCY2C at 5 μg/mL can bind Anti-GUCY2C recombinant antibody, the EC50 is 5.630-9.996 ng/mL.
2. T84 cells were stained with Human IgG (green line) and anti-GUCY2C antibody (red line) (2µg/1*10^6 cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
3. Untransfected CT26 cells surface (green line) and transfected Human GUCY2C CT26 stable cells surface (red line) were stained with anti-GUCY2C antibody (2µg/1*10^6 cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
Application
Recommended Dose
FCM:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationCell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The 145 kDa plasma membrane form of GC-C contains sialic acid and galactose residues, while a differencially glycosylated 130 Kda form is a high mannose form that is resident in the endoplasmic reticulum and may serve as the precursor for the cell surface form.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPreservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
Research BackgroundReceptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptides guanylin and uroguanylin.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human GUCY2C Protein
Antigen Species
Human
Gene Name
GUCY2C
Gene ID
Uniprot ID
Biology Area
Immunology
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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