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Anti-Tyrosinase/TYR Antibody (7Z445)

Catalog No. TMAH-01230 Copy Product Info
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Anti-Tyrosinase/TYR Antibody (7Z445) is an antibody targeting Tyrosinase/TYR. Anti-Tyrosinase/TYR Antibody (7Z445) can be used in ELISA,IF.

Anti-Tyrosinase/TYR Antibody (7Z445)

Copy Product Info
🥰Excellent
Catalog No. TMAH-01230

Anti-Tyrosinase/TYR Antibody (7Z445) is an antibody targeting Tyrosinase/TYR. Anti-Tyrosinase/TYR Antibody (7Z445) can be used in ELISA,IF.

Anti-Tyrosinase/TYR Antibody
(7Z445)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2087-10 days7-10 days
100 μL$3477-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Tyrosinase/TYR Antibody (7Z445) is an antibody targeting Tyrosinase/TYR. Anti-Tyrosinase/TYR Antibody (7Z445) can be used in ELISA,IF.
Ig Type
Rabbit IgG
Clone
7Z445
Reactivity
Human
Verified Activity
Immunofluorescence staining of MCF7 Cells with TMAH-01230 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).
Application
Recommended Dose
IF:1:20-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationMelanosome membrane; Single-pass type I membrane protein. Melanosome.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundThis is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human Tyrosinase
Antigen Species
Human
Gene Name
TYR
Gene ID
Uniprot ID
Biology Area
Cancer, Tags & Cell Markers
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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