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Anti-Tyrosinase/TYR Antibody (7Z445)
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Catalog No. TMAH-01230
Anti-Tyrosinase/TYR Antibody (7Z445) is an antibody targeting Tyrosinase/TYR. Anti-Tyrosinase/TYR Antibody (7Z445) can be used in ELISA, IF.
Anti-Tyrosinase/TYR Antibody (7Z445)
Anti-Tyrosinase/TYR Antibody (7Z445)
😃Good
Catalog No. TMAH-01230
Anti-Tyrosinase/TYR Antibody (7Z445) is an antibody targeting Tyrosinase/TYR. Anti-Tyrosinase/TYR Antibody (7Z445) can be used in ELISA, IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $208 | 7-10 days | |
| 100 μL | $347 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Recombinant Rabbit Monoclonal Application: ELISA, IF Reactivity: Human |
| Ig Type | Rabbit IgG |
| Clone | 7Z445 |
| Reactivity | Human |
| Verified Activity | Immunofluorescence staining of MCF7 Cells with TMAH-01230 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L). |
| Application | ELISA, IF |
| Recommended Dose | IF:1:20-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Melanosome membrane; Single-pass type I membrane protein. Melanosome. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human Tyrosinase |
| Antigen Species | Human |
| Gene ID | 7299 |
| Uniprot ID | |
| Biology Area | Cancer, Tags & Cell Markers |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Sci Citations
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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