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GDF-8 Protein, Human/Cynomolgus/Mouse/Rat, Recombinant (Avi), Biotinylated

(Synonyms: Myostatin, Mstn, GDF-8, GDF8) Copy Product Info

Synonyms: Myostatin, Mstn, GDF-8, GDF8

Catalog No. TMPK-01698 Copy Product Info
GDF-8 Protein, Human/Cynomolgus/Mouse/Rat, Recombinant (Avi), Biotinylated is expressed in HEK293 Cells. The accession number is O14793(Human)/Q95J86(Cynomolgus)/O08689(Mouse)/O35312(Rat).
GDF-8 Protein, Human/Cynomolgus/Mouse/Rat, Recombinant (Avi), Biotinylated
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Pack SizePriceUSA StockGlobal StockQuantity
5 µg$1827-10 days7-10 days
10 µg$2867-10 days7-10 days
20 µg$4487-10 days7-10 days
50 µg$8297-10 days7-10 days
100 µg$1,3207-10 days7-10 days
200 µg$2,0907-10 days7-10 days
500 µg$3,9207-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Immobilized Human/Cynomolgus Activin RIIB, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Human/Cynomolgus/Mouse/Rat GDF-8, Avi Tag with the EC50 of 2.5 ng/ml determined by ELISA (QC Test).
Description
GDF-8 Protein, Human/Cynomolgus/Mouse/Rat, Recombinant (Avi), Biotinylated is expressed in HEK293 Cells. The accession number is O14793(Human)/Q95J86(Cynomolgus)/O08689(Mouse)/O35312(Rat).
Species
Human/Cynomolgus/Mouse/Rat
Expression System
HEK293 Cells
TagC-Avi
Accession NumberO14793(Human)/Q95J86(Cynomolgus)/O08689(Mouse)/O35312(Rat)
ConstructionAsp267-Ser375 (Human/Cynomolgus)/Asp268-Ser376 (Mouse/Rat)
Protein Purity
> 95% as determined by Bis-Tris PAGE
Endotoxin< 1 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from 0.22 μm filtered solution in 4 mM HCL. Normally 8% trehalose is added as protectant before lyophilization.
ReconstitutionReconstitute the lyophilized protein in 4 mM HCL. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsMyostatin, Mstn, GDF-8, GDF8
Research Background
Growth/differentiation factor 8 (GDF8), or myostatin, negatively regulates muscle mass. GDF8 is held in a latent state through interactions with its N-terminal prodomain. GDF8, like numerous TGF-β family members, is a disulfidelinked dimer that is synthesized as a precursor protein which requires cleavage by a furin-like protease to yield an N-terminal prodomain and a C-terminal mature, signaling domain.
Chemical Properties
Molecular Weight14.21 kDa (Predicted); 15-18 kDa (Reducing condition, due to glycosylation)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: GDF-8 Protein, Human/Cynomolgus/Mouse/Rat, Recombinant (Avi), Biotinylated chemical structure | GDF-8 Protein, Human/Cynomolgus/Mouse/Rat, Recombinant (Avi), Biotinylated molecular weight