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Anti-HSD17B1 Antibody (6P431)

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Catalog No. TMAB-07316

Anti-HSD17B1 Antibody (6P431) is a Rabbit antibody targeting HSD17B1. Anti-HSD17B1 Antibody (6P431) can be used in WB,IHC-P,IHC-Fr,IF.

Anti-HSD17B1 Antibody (6P431)

Anti-HSD17B1 Antibody (6P431)

😃Good
Catalog No. TMAB-07316
Anti-HSD17B1 Antibody (6P431) is a Rabbit antibody targeting HSD17B1. Anti-HSD17B1 Antibody (6P431) can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4727-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-HSD17B1 Antibody (6P431) is a Rabbit antibody targeting HSD17B1. Anti-HSD17B1 Antibody (6P431) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
6P431
Reactivity
Human
Application
WB
IHC-P
IHC-Fr
IF
Recommended Dose
WB: 1:1000-5000; IHC-P: 1:1000-5000; IHC-Fr: 1:1000-5000; IF: 1:1000-5000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a member of the 17beta-hydroxysteroid dehydrogenase family of short-chain dehydrogenases/reductases. It has a dual function in estrogen activation and androgen inactivation and plays a major role in establishing the estrogen E2 concentration gradient between serum and peripheral tissues. The encoded protein catalyzes the last step in estrogen activation, using NADPH to convert estrogens E1 and E2 and androgens like 4-androstenedione, to testosterone. It has an N-terminal short-chain dehydrogenase domain with a cofactor binding site, and a narrow, hydrophobic C-terminal domain with a steroid substrate binding site. This gene is expressed primarily in the placenta and ovarian granulosa cells, and to a lesser extent, in the endometrium, adipose tissue, and prostate. Polymorphisms in this gene have been linked to breast and prostate cancer. A pseudogene of this gene has been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human HSD17B1
Antigen Species
Human
Gene Name
HSD17B1
Gene ID
3292
Protein Name
17-beta-hydroxysteroid dehydrogenase type 1
Uniprot ID
P14061
Function
Favors the reduction of estrogens and androgens. Also has 20-alpha-HSD activity. Uses preferentially NADH.
Chemical Properties
Molecular WeightTheoretical: 35 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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