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Anti-HMGCL Antibody (1O857)
Catalog No. TMAB-07187 Copy Product Info
🥰Excellent
Anti-HMGCL Antibody (1O857) is a Rabbit antibody targeting HMGCL. Anti-HMGCL Antibody (1O857) can be used in IF, IHC-Fr, IHC-P.
Anti-HMGCL Antibody (1O857)
Copy Product Info🥰Excellent
Catalog No. TMAB-07187
Anti-HMGCL Antibody (1O857) is a Rabbit antibody targeting HMGCL. Anti-HMGCL Antibody (1O857) can be used in IF, IHC-Fr, IHC-P.
Anti-HMGCL Antibody
(1O857)
(1O857)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-HMGCL Antibody (1O857) is a Rabbit antibody targeting HMGCL. Anti-HMGCL Antibody (1O857) can be used in IF, IHC-Fr, IHC-P. |
| Ig Type | IgG |
| Clone | 1O857 |
| Reactivity | Human |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded Human Colon Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with HMGCL Monoclonal Antibody, Unconjugated (TMAB-07187) at 1:200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L-HRP and DAB staining. 2. Paraformaldehyde-fixed, paraffin embedded Human Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with HMGCL Monoclonal Antibody, Unconjugated (TMAB-07187) at 1:200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L-HRP and DAB staining. 3. Paraformaldehyde-fixed, paraffin embedded Human Testicles; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with HMGCL Monoclonal Antibody, Unconjugated (TMAB-07187) at 1:200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L-HRP and DAB staining. 4. Paraformaldehyde-fixed, paraffin embedded Human Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with HMGCL Monoclonal Antibody, Unconjugated (TMAB-07187) at 1:200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L-HRP and DAB staining. 5. Paraformaldehyde-fixed, paraffin embedded Human Pancreas; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with HMGCL Monoclonal Antibody, Unconjugated (TMAB-07187) at 1:200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L-HRP and DAB staining. |
| Application | |
| Recommended Dose | IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion matrix. |
| Tissue Specificity | Fibroblasts, liver and lymphoblasts. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism. |
| Immunogen | A synthesized peptide: human HMGCL |
| Antigen Species | Human |
| Gene Name | HMGCL |
| Gene ID | |
| Protein Name | Hydroxymethylglutaryl-CoA lyase, mitochondrial |
| Uniprot ID | |
| Function | Key enzyme in ketogenesis (ketone body formation). Terminal step in leucine catabolism. |
| Molecular Weight | Theoretical: 34 kDa. Actual: 30 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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