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Anti-HDAC2 Antibody (5Z519) (Synonyms: Histone deacetylase 2, HDAC 2, HD2, EC 3.5.1.98)

Catalog No. TMAC-01774 Copy Product Info
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Anti-HDAC2 Antibody (5Z519) is a Rabbit antibody targeting HDAC2. Anti-HDAC2 Antibody (5Z519) can be used in IP,WB.

Anti-HDAC2 Antibody (5Z519)

Copy Product Info
🥰Excellent
Catalog No. TMAC-01774
Synonyms Histone deacetylase 2, HDAC 2, HD2, EC 3.5.1.98

Anti-HDAC2 Antibody (5Z519) is a Rabbit antibody targeting HDAC2. Anti-HDAC2 Antibody (5Z519) can be used in IP,WB.

Anti-HDAC2 Antibody
(5Z519)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-HDAC2 Antibody (5Z519) is a Rabbit antibody targeting HDAC2. Anti-HDAC2 Antibody (5Z519) can be used in IP,WB.
SynonymsHistone deacetylase 2, HDAC 2, HD2, EC 3.5.1.98
Ig Type
IgG
Clone
5Z519
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of HDAC2 on different lysates using anti-HDAC2 antibody at 1/1,000 dilution. Positive control: Lane 1: K562, Lane 2: Hela.
verifiedActivity
Application
Recommended Dose
WB: 1:1000-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundIn the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (for p300/CBP-associated factor), p300/CBP and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1) and HDAC2 (also designated mammalian RPD3), both of which are related to the yeast transcriptional regulator Rpd3p, have been identified as histone deacetylases.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 60 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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