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Anti-MRP2 Antibody (3I477)

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Catalog No. TMAB-08996

Anti-MRP2 Antibody (3I477) is a Rabbit antibody targeting MRP2. Anti-MRP2 Antibody (3I477) can be used in FCM,IHC-P,IHC-Fr,IF.

Anti-MRP2 Antibody (3I477)

Anti-MRP2 Antibody (3I477)

😃Good
Catalog No. TMAB-08996
Anti-MRP2 Antibody (3I477) is a Rabbit antibody targeting MRP2. Anti-MRP2 Antibody (3I477) can be used in FCM,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2637-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-MRP2 Antibody (3I477) is a Rabbit antibody targeting MRP2. Anti-MRP2 Antibody (3I477) can be used in FCM,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
3I477
Reactivity
Human
Application
FCM
IHC-P
IHC-Fr
IF
Recommended Dose
FCM: 1μg/Test; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Multi-pass membrane protein.
Tissue SpecificityFound on the apical membrane of polarized cells in liver, kidney and intestine. The highest expression is found in liver.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research Backgroundmultidrug resistance-associated protein 2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. Belongs to the ABC transporter family.
Antigen Details
Immunogen
A synthesized peptide: human ABCC2
Antigen Species
Human
Gene Name
ABCC2
Gene ID
1244
Protein Name
Canalicular multispecific organic anion transporter 1
Uniprot ID
Q92887
Function
Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter.
Chemical Properties
Molecular WeightTheoretical: 174 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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