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Anti-KRT6A Antibody (4G523)
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Catalog No. TMAC-01092
Alias Type-II keratin Kb6, type II cytoskeletal 6A, KRT 6A, Keratin-6A, Keratin, K6A KRT6D, K6A, Cytokeratin-6D, Cytokeratin-6A, CK-6D, CK-6A
Anti-KRT6A Antibody (4G523) is a Rabbit antibody targeting KRT6A. Anti-KRT6A Antibody (4G523) can be used in ICC/IF,IHC,WB.
Anti-KRT6A Antibody (4G523)
Anti-KRT6A Antibody (4G523)
😃Good
Catalog No. TMAC-01092Alias Type-II keratin Kb6, type II cytoskeletal 6A, KRT 6A, Keratin-6A, Keratin, K6A KRT6D, K6A, Cytokeratin-6D, Cytokeratin-6A, CK-6D, CK-6A
Anti-KRT6A Antibody (4G523) is a Rabbit antibody targeting KRT6A. Anti-KRT6A Antibody (4G523) can be used in ICC/IF,IHC,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $296 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-KRT6A Antibody (4G523) is a Rabbit antibody targeting KRT6A. Anti-KRT6A Antibody (4G523) can be used in ICC/IF,IHC,WB. |
| Synonyms | Type-II keratin Kb6, type II cytoskeletal 6A, KRT 6A, Keratin-6A, Keratin, K6A KRT6D, K6A, Cytokeratin-6D, Cytokeratin-6A, CK-6D, CK-6A |
| Ig Type | IgG |
| Clone | 4G523 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of Cytokeratin 6 on human skin lysates using anti-Cytokeratin 6 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Cytokeratin 6 antibody. Counter stained with hematoxylin. 3. ICC staining Cytokeratin 6 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue, where they constitute up to 85% of mature keratinocytes in the vertebrate epidermis. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. The alpha-helical coiled-coil dimers associate laterally end-to-end to form 10 nm diameter filaments. Cytokeratins, which are useful markers of tissue differentiation, also aid in the characterization of malignant tumors. IL-1 and TNFα induce transcription of cytokeratin 6 in epidermal keratinocytes via the C/EBP β transcription factor. In humans, multiple isoforms of cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns, and cytokeratin 6A is the dominant form in epithelial tissue. The gene encoding human cytokeratin 6A maps to chromosome 12q13, and mutations in this gene are linked to several inheritable hair and skin pathologies. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 60 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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