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Anti-ITGAV Antibody (7U37)
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Catalog No. TMAC-02177
Alias VTNR, VNRA, Vitronectin receptor subunit alpha, Vitronectin receptor, MSK8, Integrin alpha-V, CD antigen CD51
Anti-ITGAV Antibody (7U37) is a Rabbit antibody targeting ITGAV. Anti-ITGAV Antibody (7U37) can be used in FCM,WB.
Anti-ITGAV Antibody (7U37)
Anti-ITGAV Antibody (7U37)
😃Good
Catalog No. TMAC-02177Alias VTNR, VNRA, Vitronectin receptor subunit alpha, Vitronectin receptor, MSK8, Integrin alpha-V, CD antigen CD51
Anti-ITGAV Antibody (7U37) is a Rabbit antibody targeting ITGAV. Anti-ITGAV Antibody (7U37) can be used in FCM,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-ITGAV Antibody (7U37) is a Rabbit antibody targeting ITGAV. Anti-ITGAV Antibody (7U37) can be used in FCM,WB. |
| Synonyms | VTNR, VNRA, Vitronectin receptor subunit alpha, Vitronectin receptor, MSK8, Integrin alpha-V, CD antigen CD51 |
| Ig Type | IgG |
| Clone | 7U37 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of Integrin alpha V+beta 6 on different lysates using anti-Integrin alpha V+beta 6 antibody at 1/1,000 dilution. Positive control: Lane 1: A549, Lane 2: PC-12. 2. Flow cytometric analysis of MCF-7 cells with Integrin alpha V antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| Application | |
| Recommended Dose | WB: 1:1000-2000; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen and vitronectin. Certain integrins can also bind to soluble ligands, such as fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 86/125 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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