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Anti-ADAMTS13 Antibody (1C436) (Synonyms: vWFCP, vWF-cleaving protease), von Willebrand factor-cleaving protea...)

Catalog No. TMAC-00087 Copy Product Info
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Anti-ADAMTS13 Antibody (1C436) is a Rabbit antibody targeting ADAMTS13. Anti-ADAMTS13 Antibody (1C436) can be used in FCM,IHC,WB.

Anti-ADAMTS13 Antibody (1C436)

Copy Product Info
🥰Excellent
Catalog No. TMAC-00087
Synonyms vWFCP, vWF-cleaving protease), von Willebrand factor-cleaving protease (vWF-CP, Gm710, ADAMTS-13, ADAM-TS13, Adamts13, ADAM-TS 13

Anti-ADAMTS13 Antibody (1C436) is a Rabbit antibody targeting ADAMTS13. Anti-ADAMTS13 Antibody (1C436) can be used in FCM,IHC,WB.

Anti-ADAMTS13 Antibody
(1C436)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4967-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ADAMTS13 Antibody (1C436) is a Rabbit antibody targeting ADAMTS13. Anti-ADAMTS13 Antibody (1C436) can be used in FCM,IHC,WB.
SynonymsvWFCP, vWF-cleaving protease), von Willebrand factor-cleaving protease (vWF-CP, Gm710, ADAMTS-13, ADAM-TS13, Adamts13, ADAM-TS 13
Ig Type
IgG
Clone
1C436
Reactivity
Human
Verified Activity
1. Western blot analysis of ADAMTS13 on SiHa cell (1), PC-3M cell (2) and A549 cell lysates using anti-ADAMTS13 antibody at 1/500 dilution.
2. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-ADAMTS13 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-ADAMTS13 antibody. Counter stained with hematoxylin.
4. Flow cytometric analysis of HepG2 cells with ADAMTS13 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
verifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13)??also known as von Willebrand factor-cleaving protease (VWFCP)??is a zinc-containing metalloprotease enzyme that cleaves von Willebrand factor (vWf), a large protein involved in blood clotting. It is secreted in blood and degrades large vWf multimers, decreasing their activity. Glycosylated. O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus sequence C1-X2-(S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine residue of the repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a beta-1,3-glucose residue by the glucosyltransferase, B3GALTL.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: human ADAMTS13 aa 150-350
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 154 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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