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Anti-TLR9 Antibody (6N996)

Catalog No. TMAB-13576 Copy Product Info
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Anti-TLR9 Antibody (6N996) is a Rabbit antibody targeting TLR9. Anti-TLR9 Antibody (6N996) can be used in WB.

Anti-TLR9 Antibody (6N996)

Copy Product Info
🥰Excellent
Catalog No. TMAB-13576

Anti-TLR9 Antibody (6N996) is a Rabbit antibody targeting TLR9. Anti-TLR9 Antibody (6N996) can be used in WB.

Anti-TLR9 Antibody
(6N996)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1497-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-TLR9 Antibody (6N996) is a Rabbit antibody targeting TLR9. Anti-TLR9 Antibody (6N996) can be used in WB.
Ig Type
IgG
Clone
6N996
Reactivity
Human
Verified Activity
Western blot analysis of Raji cell lysate. Using TLR9 (TMAB-13576) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:1000-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationEndoplasmic reticulum membrane; Single-pass type I membrane protein. Endosome. Lysosome. Cytoplasmic vesicle, phagosome. Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.
Tissue SpecificityHighly expressed in spleen, lymph node, tonsil and peripheral blood leukocytes, especially in plasmacytoid pre-dendritic cells. Levels are much lower in monocytes and CD11c+ immature dendritic cells. Also detected in lung and liver.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundKey component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides.Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Antigen Details
Immunogen
A synthesized peptide: human TLR9
Antigen Species
Human
Gene Name
TLR9
Gene ID
Protein Name
Toll-like receptor 9
Uniprot ID
Function
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Controls lymphocyte response to Helicobacter infection.
Chemical Properties
Molecular WeightTheoretical: 116 kDa. Actual: 130 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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