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Anti-Phospho-MAPT/Tau (Ser404) Antibody (5I292)
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Catalog No. TMAB-10947
Anti-Phospho-MAPT/Tau (Ser404) Antibody (5I292) is a Rabbit antibody targeting Phospho-MAPT/Tau (Ser404). Anti-Phospho-MAPT/Tau (Ser404) Antibody (5I292) can be used in WB,IHC-P,IHC-Fr,IF.
Anti-Phospho-MAPT/Tau (Ser404) Antibody (5I292)
Anti-Phospho-MAPT/Tau (Ser404) Antibody (5I292)
😃Good
Catalog No. TMAB-10947
Anti-Phospho-MAPT/Tau (Ser404) Antibody (5I292) is a Rabbit antibody targeting Phospho-MAPT/Tau (Ser404). Anti-Phospho-MAPT/Tau (Ser404) Antibody (5I292) can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-MAPT/Tau (Ser404) Antibody (5I292) is a Rabbit antibody targeting Phospho-MAPT/Tau (Ser404). Anti-Phospho-MAPT/Tau (Ser404) Antibody (5I292) can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Clone | 5I292 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Note=Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components. |
| Tissue Specificity | Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Concentration | 1mg/ml |
| Research Background | Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system. |
| Immunogen | A synthesized peptide: human Tau around the phosphorylation site of S404 |
| Antigen Species | Human |
| Gene Name | MAPT |
| Gene ID | |
| Protein Name | Microtubule-associated protein tau |
| Uniprot ID | |
| Function | Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. |
| Molecular Weight | Theoretical: 79 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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