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Anti-FOXO1A Antibody (2K180)
Catalog No. TMAB-06133 Copy Product Info
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Anti-FOXO1A Antibody (2K180) is a Rabbit antibody targeting FOXO1A. Anti-FOXO1A Antibody (2K180) can be used in WB.
Anti-FOXO1A Antibody (2K180)
Copy Product Info🥰Excellent
Catalog No. TMAB-06133
Anti-FOXO1A Antibody (2K180) is a Rabbit antibody targeting FOXO1A. Anti-FOXO1A Antibody (2K180) can be used in WB.
Anti-FOXO1A Antibody
(2K180)
(2K180)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-FOXO1A Antibody (2K180) is a Rabbit antibody targeting FOXO1A. Anti-FOXO1A Antibody (2K180) can be used in WB. |
| Ig Type | IgG |
| Clone | 2K180 |
| Reactivity | Human |
| Verified Activity | 25 μg total protein per lane of various lysates (see on figure) probed with FOXO1A monoclonal antibody, unconjugated (TMAB-06133) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Nucleus. Note=Shuttles between cytoplasm and nucleus. Translocates to the nucleus upon oxidative stress induced phosphorylation at Ser-212 by STK4/MST1. Translocates to the nucleus upon phosphorylation of Thr-24, Ser-256 and Ser-322 by SGK1. |
| Tissue Specificity | Ubiquitous. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq]. |
| Immunogen | A synthesized peptide: human FOXO1 |
| Antigen Species | Human |
| Gene Name | FOXO1 |
| Gene ID | |
| Protein Name | Forkhead box protein O1 |
| Uniprot ID | |
| Function | Transcription factor which acts as a regulator of cell responses to oxidative stress. In the presence of KIRT1, mediates down-regulation of cyclin D1 and up-regulation of CDKN1B levels which are required for cell transition from proliferative growth to quiescence. Triggers death of postmitotic neurons when phosphorylated by CDK1. Activates transcription of PMAIP1. |
| Molecular Weight | Theoretical: 72 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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