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Anti-PHB2 Antibody (1Q737)
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Catalog No. TMAB-10258
Anti-PHB2 Antibody (1Q737) is a Rabbit antibody targeting PHB2. Anti-PHB2 Antibody (1Q737) can be used in WB,ICC/IF.
Anti-PHB2 Antibody (1Q737)
Anti-PHB2 Antibody (1Q737)
Copy Product Info😃Good
Catalog No. TMAB-10258
Anti-PHB2 Antibody (1Q737) is a Rabbit antibody targeting PHB2. Anti-PHB2 Antibody (1Q737) can be used in WB,ICC/IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
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| Description | Anti-PHB2 Antibody (1Q737) is a Rabbit antibody targeting PHB2. Anti-PHB2 Antibody (1Q737) can be used in WB,ICC/IF. |
| Ig Type | IgG/Kappa |
| Clone | 1Q737 |
| Reactivity | Human (predicted:Mouse,Rat) |
| Verified Activity | 1. Blocking buffer: 5% NFDM/TBST Primary ab dilution: 1:10000 Primary ab incubation condition: 2 hours at room temperature Secondary ab: Goat Anti-Rabbit IgG H&L (HRP) Lysate: HeLa, 293, Mouse heart, Rat kidney Protein loading quantity: 20 μg Exposure time: 30 s Predicted MW: 33 kDa Observed MW: 33 kDa 2. Cell line: HeLa Fixative: 100% Ice-cold methanol Permeabilization: 0.1% TritonX-100 Primary ab dilution: 1:50 Primary incubation condition: 4°C overnight Secondary ab: Goat Anti-Rabbit IgG Nuclear counter stain: DAPI (Blue) Comment: Color green is the positive signal for TMAB-10258 |
| Application | |
| Recommended Dose | WB: 1:2000-10000; ICC/IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion inner membrane. Cytoplasm. Nucleus. Also cytoplasmic and nuclear. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Enables several functions, including protein C-terminus binding activity; protein N-terminus binding activity; and protein dimerization activity. Involved in several processes, including defense response to virus; positive regulation of cell cycle phase transition; and regulation of transcription, DNA-templated. Located in several cellular components, including cell surface; mitochondrial membrane; and nuclear matrix. Part of mitochondrial prohibitin complex. [provided by Alliance of Genome Resources, Apr 2022] |
| Gene Name | PHB2 |
| Gene ID | |
| Protein Name | Prohibitin-2 |
| Function | Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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